Gene: GAS8
Official Full Name: dynein regulatory complex subunit 4provided by HGNC
Gene Summary: This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37717 | GAS8 Knockout cell line (HeLa) | Human | GAS8 | 1:3~1:6 | Negative | Online Inquiry |
KO37718 | GAS8 Knockout cell line (HCT 116) | Human | GAS8 | 1:2~1:4 | Negative | Online Inquiry |
KO37719 | GAS8 Knockout cell line (HEK293) | Human | GAS8 | 1:3~1:6 | Negative | Online Inquiry |
KO37720 | GAS8 Knockout cell line (A549) | Human | GAS8 | 1:3~1:4 | Negative | Online Inquiry |
GAS8 Gene Knockout Cell Lines represent a critical innovation in molecular biology, providing researchers with genetically modified cellular models where the GAS8 gene has been precisely disrupted. The GAS8 gene is believed to play significant roles in cellular processes, including growth regulation and apoptosis. By studying these knockout cell lines, scientists can delve into the specific functions and pathways influenced by GAS8, offering insights into not only basic cellular biology but also its implications in various disease states.
The fundamental mechanism of GAS8 Gene Knockout Cell Lines involves targeted gene editing technologies, such as CRISPR/Cas9, which enable the precise alteration of the GAS8 locus, resulting in the knockout of its expression. This methodological approach allows for the examination of functional outcomes related to GAS8 deficiency, including potential impacts on cell proliferation, signaling pathways, and interactions with other genes and proteins. Consequently, these cell lines serve as valuable tools in dissecting complex biological phenomena and pathophysiological conditions.
From a scientific perspective, the implications of using GAS8 Gene Knockout Cell Lines are profound, particularly in cancer research, developmental biology, and therapeutic development. By elucidating the role of GAS8, researchers could identify novel therapeutic targets, paving the way for innovative approaches to cancer treatment or other diseases where GAS8 may be implicated.
Compared to conventional cell lines or non-targeted experimental models, our GAS8 Gene Knockout Cell Lines offer a unique advantage: specificity. Unlike alternative models that may inadvertently retain functionality or present compensatory mechanisms, these lines ensure a clean knockout, providing clearer interpretations of results. Additionally, they are rigorously validated, ensuring consistency and reliability in experimental outcomes.
For researchers and clinicians alike, the GAS8 Gene Knockout Cell Lines present an unparalleled resource for advancing understanding in genomic and cellular dynamics, facilitating groundbreaking research that can drive clinical innovations. By partnering with us, users not only gain access to these cutting-edge products but align with a company renowned for its expertise in genetic engineering and a commitment to enhancing scientific exploration.
Please note that all services are for research use only. Not intended for any clinical use.
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