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GAREM2 Knockout Cell Lines

Gene: GAREM2

Official Full Name: GRB2 associated regulator of MAPK1 subtype 2provided by HGNC

Gene Summary: Predicted to act upstream of or within several processes, including cognition; neuron projection extension; and social behavior. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22019 GAREM2 Knockout cell line (HeLa) Human GAREM2 1:3~1:6 Negative Online Inquiry
KO22020 GAREM2 Knockout cell line (HCT 116) Human GAREM2 1:2~1:4 Negative Online Inquiry
KO22021 GAREM2 Knockout cell line (HEK293) Human GAREM2 1:3~1:6 Negative Online Inquiry
KO22022 GAREM2 Knockout cell line (A549) Human GAREM2 1:3~1:4 Negative Online Inquiry

Background

GAREM2 Gene Knockout Cell Lines are genetically modified cell lines that have had the GAREM2 gene purposefully disrupted, enabling researchers to study the gene's function and its contribution to various cellular processes. This advanced biological product serves as an indispensable tool for delineating gene roles in signaling pathways, cellular differentiation, and disease mechanisms, particularly in cancer research and developmental biology.

The primary function of GAREM2 Gene Knockout Cell Lines is to facilitate the investigation of GAREM2's role in cellular processes by removing its expression. This is achieved through the utilization of CRISPR-Cas9 technology, which introduces targeted double-strand breaks in the DNA, leading to gene disruption during repair. As a result, researchers are equipped to analyze phenotypic changes, alterations in proliferation, apoptosis, and differentiation pathways in these knockout cells compared to wild-type controls.

The scientific importance of GAREM2 Gene Knockout Cell Lines lies in their applicability across various research fields, including oncology and molecular biology. By elucidating the functions of GAREM2, researchers can potentially uncover novel therapeutic targets for diseases where this gene is implicated, significantly advancing our understanding of pathophysiology and paving the way for innovative treatment strategies.

Moreover, GAREM2 Gene Knockout Cell Lines distinguish themselves from conventional cell models by offering a more accurate representation of gene function in a controlled environment. Unlike random integration methods, the precise editing permitted by CRISPR ensures reproducibility and reliability in experimental outcomes. This enhanced specificity not only provides higher confidence in results but also constrains the off-target effects commonly seen with alternative gene-editing technologies.

For researchers and clinicians, the value of GAREM2 Gene Knockout Cell Lines cannot be overstated. Their capacity to enable in-depth studies of gene function accelerates the pace of discovery, fostering innovation and translating findings into clinical applications more effectively. By utilizing these knockout models, investigators can generate crucial insights that drive advancements in therapeutic development.

At [Company Name], we are committed to providing high-quality genetic engineering solutions tailored to the needs of the scientific community. With our expertise in gene editing technologies and comprehensive support, we equip researchers with the tools necessary to push the boundaries of discovery and innovation in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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