Gene: GAPVD1
Official Full Name: GTPase activating protein and VPS9 domains 1provided by HGNC
Gene Summary: Enables GTPase activating protein binding activity and guanyl-nucleotide exchange factor activity. Involved in regulation of protein transport. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28294 | GAPVD1 Knockout cell line (HeLa) | Human | GAPVD1 | 1:3~1:6 | Negative | Online Inquiry |
KO28295 | GAPVD1 Knockout cell line (HCT 116) | Human | GAPVD1 | 1:2~1:4 | Negative | Online Inquiry |
KO28296 | GAPVD1 Knockout cell line (HEK293) | Human | GAPVD1 | 1:3~1:6 | Negative | Online Inquiry |
KO28297 | GAPVD1 Knockout cell line (A549) | Human | GAPVD1 | 1:3~1:4 | Negative | Online Inquiry |
GAPVD1 Gene Knockout Cell Lines are genetically engineered models specifically designed to study the role of the GAPVD1 gene in cellular processes and disease states. These cell lines are generated using CRISPR-Cas9 technology, which introduces targeted deletions in the GAPVD1 gene, allowing researchers to observe the resultant phenotypic changes without the functional contributions of this gene. By offering a precise knockout of GAPVD1, these cell lines become indispensable tools for delineating its biological functions in various signaling pathways, including those related to cytoskeletal dynamics and cellular adhesion.
The key functioning mechanism of the GAPVD1 knockout involves the loss of protein interactions that are critical for cellular responsiveness to extracellular stimuli. This disruption offers a unique opportunity to investigate the gene's involvement in mechanotransduction, apoptosis, and tumorigenesis, making the cell lines particularly valuable for cancer research and therapeutic development. Such models have significant implications in understanding tumor biology, drug resistance, and potential therapeutic targets.
In scientific contexts, these cell lines can be pivotal for both basic and translational research. They enable researchers to investigate cellular responses and pathways in a controlled environment, thus expediting the discovery of new treatments or interventions. Unlike traditional methods, our GAPVD1 Gene Knockout Cell Lines provide a streamlined, reproducible model that saves time and enhances the reliability of experimental outcomes.
The distinct advantages of our GAPVD1 knockout models lie in their reliability, ease of use, and the comprehensive support provided for experimental design and analysis. Additionally, the specificity of the gene knockout minimizes off-target effects, which is crucial for obtaining robust data that can be easily translated to clinical applications.
Our company specializes in advanced genetic engineering technologies and is committed to delivering high-quality biological products that meet the rigorous demands of researchers and clinicians. By choosing our GAPVD1 Gene Knockout Cell Lines, you not only gain access to a cutting-edge research tool but also benefit from our expertise and dedication to supporting scientific advancement.
Please note that all services are for research use only. Not intended for any clinical use.
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