Gene: GALNTL6
Official Full Name: polypeptide N-acetylgalactosaminyltransferase like 6provided by HGNC
Gene Summary: Enables polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17471 | GALNTL6 Knockout cell line (HeLa) | Human | GALNTL6 | 1:3~1:6 | Negative | Online Inquiry |
GALNTL6 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to lack the GALNTL6 gene, which encodes an essential glycosyltransferase involved in the modification of glycoproteins. The knockout of this gene allows researchers to investigate the role of GALNTL6 in various biological processes, particularly its influence on glycosylation patterns, which are crucial for protein function and cellular interactions. By employing CRISPR-Cas9 technology, these cell lines are created with precision, ensuring complete and stable gene disruption.
The primary function of GALNTL6 Gene Knockout Cell Lines is to enable scientists to assess the physiological consequences of GALNTL6 deficiency, helping elucidate its role in diseases where aberrant glycosylation is implicated, such as cancer and metabolic disorders. In particular, these cell lines can improve our understanding of tumor microenvironments, immune evasion, and cellular signaling pathways. Such insights are critical for developing targeted therapies and personalized medicine approaches.
In comparison to alternative models or methods for studying glycosylation, these knockout cell lines offer several distinct advantages. They provide a consistent and reproducible platform for experiments, reducing variability often associated with primary cell cultures. Additionally, the use of knockout models allows for a more accurate representation of gene function in vivo, providing clearer data for downstream applications such as drug testing and biomarker discovery.
For researchers and clinicians, the GALNTL6 Gene Knockout Cell Lines present significant value by offering a reliable tool for probing the complexities of glycosylation-related biological phenomena. Their accessibility and the wealth of information they can generate contribute to a deeper understanding of health and disease mechanisms.
At our company, we pride ourselves on our commitment to advancing biological research through high-quality products that facilitate groundbreaking discoveries. With our expertise in genetic engineering and cell line development, we provide researchers with innovative tools necessary for the exploration of critical biological questions.
Please note that all services are for research use only. Not intended for any clinical use.
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