Gene: GALNT11
Official Full Name: polypeptide N-acetylgalactosaminyltransferase 11provided by HGNC
Gene Summary: Enables Notch binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17481 | GALNT11 Knockout cell line (HeLa) | Human | GALNT11 | 1:3~1:6 | Negative | Online Inquiry |
KO17482 | GALNT11 Knockout cell line (HCT 116) | Human | GALNT11 | 1:2~1:4 | Negative | Online Inquiry |
KO17483 | GALNT11 Knockout cell line (HEK293) | Human | GALNT11 | 1:3~1:6 | Negative | Online Inquiry |
KO17484 | GALNT11 Knockout cell line (A549) | Human | GALNT11 | 1:3~1:4 | Negative | Online Inquiry |
GALNT11 Gene Knockout Cell Lines are specialized cellular models engineered to disrupt the function of the GALNT11 gene, which encodes a glycosyltransferase involved in the biosynthesis of O-linked glycans. These knockout cell lines serve as vital tools for studying the physiological and pathological roles of GALNT11, particularly its contributions to cancer progression, metabolic disorders, and other critical biological processes. By eliminating the expression of the GALNT11 protein, researchers can readily investigate the downstream effects on cellular signaling pathways and metabolic functions.
The primary function of these cell lines lies in their ability to elucidate the molecular mechanisms through which GALNT11 influences cellular behavior. Utilization of CRISPR-Cas9 technology ensures precise gene editing, allowing for effective gene knockout and subsequent analysis of phenotypic changes. This specificity enables researchers to confidently attribute observed alterations in cell proliferation, migration, and response to therapeutic agents directly to the absence of GALNT11 function.
In academic and clinical research settings, GALNT11 knockout cell lines are invaluable for the development of targeted therapies and personalized medicine approaches. By providing a model that accurately reflects GALNT11’s role in disease processes, these cell lines facilitate investigations into potential biomarkers and therapeutic targets, ultimately contributing to improved clinical outcomes.
Compared to alternative models, GALNT11 knockout cell lines offer distinct advantages, including high levels of genomic accuracy, reproducibility, and the capability for high-throughput screening. This allows research teams to conduct experiments more efficiently and with greater confidence in their results.
For researchers and clinicians committed to advancing knowledge in cell biology and disease mechanisms, GALNT11 Gene Knockout Cell Lines represent a powerful and essential resource. With a focus on quality and scientific rigor, our company brings years of expertise in developing cutting-edge biological tools, ensuring that our products meet the high standards required in sophisticated research environments.
Please note that all services are for research use only. Not intended for any clinical use.
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