Gene: GAGE5
Official Full Name: G antigen 5provided by HGNC
Gene Summary: This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37765 | GAGE5 Knockout cell line (HeLa) | Human | GAGE5 | 1:3~1:6 | Negative | Online Inquiry |
KO37766 | GAGE5 Knockout cell line (HCT 116) | Human | GAGE5 | 1:2~1:4 | Negative | Online Inquiry |
KO37767 | GAGE5 Knockout cell line (HEK293) | Human | GAGE5 | 1:3~1:6 | Negative | Online Inquiry |
KO37768 | GAGE5 Knockout cell line (A549) | Human | GAGE5 | 1:3~1:4 | Negative | Online Inquiry |
GAGE5 Gene Knockout Cell Lines represent a significant advancement in genetic research, specifically tailored to study the GAGE5 gene’s role in various cellular processes. These cell lines are meticulously engineered through the CRISPR-Cas9 gene editing technology to definitively eliminate the expression of the GAGE5 gene, providing a controlled environment to investigate its biological functions and interactions. By employing these knockout cell lines, researchers can delve deeper into the molecular mechanisms underlying cancer progression, immune response, and other physiological processes associated with GAGE5 activity.
The key mechanism of GAGE5 Gene Knockout Cell Lines revolves around the CRISPR-Cas9 system, which allows for precise modifications in the genome. The deletion of the GAGE5 gene not only aids in elucidating its pathway but also enables researchers to assess downstream effects on associated signaling cascades or gene expression profiles. This is particularly crucial in research areas such as tumor immunology and therapeutic development, where the understanding of tumor antigens like GAGE5 can influence treatment responses.
In both research and clinical settings, GAGE5 Gene Knockout Cell Lines hold immense scientific importance. They facilitate high-throughput screening of potential therapeutic agents, allowing scientists to identify compounds that may target the cellular mechanisms governed by GAGE5. Furthermore, these cell lines serve as a platform for validating the efficacy of novel immunotherapies aimed at cancers expressing GAGE5, thus bridging the gap between basic research and clinical application.
Compared to alternative cell lines, the GAGE5 Gene Knockout Cell Lines are uniquely designed to provide specificity in studying the GAGE5 gene without the confounding effects of other genes. Their robust performance in experimental setups, combined with their validated knockout status, ensures reliable results, enhancing the reproducibility of scientific studies.
For researchers and clinicians alike, the GAGE5 Gene Knockout Cell Lines are invaluable tools that promise to expand our understanding of diseases and foster the development of targeted therapies. Their strategic application can drive innovation and accelerate breakthroughs in life sciences.
At our company, we pride ourselves on our expertise in genetic engineering and the production of high-quality biological products, ensuring that researchers have access to the tools they need to push the boundaries of scientific inquiry and advance therapeutic frontiers.
Please note that all services are for research use only. Not intended for any clinical use.
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