Gene: GAGE12I
Official Full Name: G antigen 12Iprovided by HGNC
Gene Summary: This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YYWPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28002 | GAGE12I Knockout cell line (HeLa) | Human | GAGE12I | 1:3~1:6 | Negative | Online Inquiry |
KO28003 | GAGE12I Knockout cell line (HCT 116) | Human | GAGE12I | 1:2~1:4 | Negative | Online Inquiry |
KO28004 | GAGE12I Knockout cell line (HEK293) | Human | GAGE12I | 1:3~1:6 | Negative | Online Inquiry |
KO28005 | GAGE12I Knockout cell line (A549) | Human | GAGE12I | 1:3~1:4 | Negative | Online Inquiry |
GAGE12I Gene Knockout Cell Lines represent a cutting-edge tool for investigating gene function and exploring the implications of gene knockout in various biological processes. These specifically engineered cell lines feature targeted deletions of the GAGE12I gene, enabling researchers to study the downstream effects of gene loss on cellular behavior, signaling pathways, and disease mechanisms.
The primary function of these knockout cell lines is to facilitate functional genomics studies that provide insights into gene regulation, cell differentiation, and the development of specific phenotypes. By creating a controlled environment where the GAGE12I gene is selectively absent, researchers can elucidate its role in diseases such as cancer, where aberrations in gene expression are often observed. The knockout approach enhances the understanding of pathogenic processes and paves the way for potential therapeutic interventions.
Scientifically, the GAGE12I Gene Knockout Cell Lines have significant applications in both research and clinical settings. They can be utilized in drug discovery programs, where the impact of new compounds on cell survival or growth can be measured, and in biomarker identification, where the absence of the GAGE12I gene may correlate with specific clinical outcomes.
What distinguishes GAGE12I Gene Knockout Cell Lines from alternative models is their precise genetic modification, validated through rigorous molecular techniques such as CRISPR-Cas9. This level of specificity allows for reliable reproducibility and data integrity, making them an invaluable resource in experimental design. Additionally, we ensure that our cell lines come with comprehensive user manuals and technical support to streamline their integration into ongoing projects.
Researchers and clinicians alike will find that the GAGE12I Gene Knockout Cell Lines significantly bolster the exploration of fundamental biological questions, enabling meaningful advancements in translational research.
At our company, we pride ourselves on delivering high-quality biological products backed by years of expertise and innovation in genomic technologies. As we continue to support the scientific community, our commitment to excellence ensures that you receive only the best tools for your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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