Gene: G3BP2
Official Full Name: G3BP stress granule assembly factor 2provided by HGNC
Gene Summary: Enables molecular condensate scaffold activity. Involved in positive regulation of stress granule assembly; protein homooligomerization; and stress granule assembly. Located in cytoplasmic stress granule and cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17503 | G3BP2 Knockout cell line (HeLa) | Human | G3BP2 | 1:3~1:6 | Negative | Online Inquiry |
KO17504 | G3BP2 Knockout cell line (HCT 116) | Human | G3BP2 | 1:2~1:4 | Negative | Online Inquiry |
KO17505 | G3BP2 Knockout cell line (HEK293) | Human | G3BP2 | 1:3~1:6 | Negative | Online Inquiry |
KO17506 | G3BP2 Knockout cell line (A549) | Human | G3BP2 | 1:3~1:4 | Negative | Online Inquiry |
G3BP2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the function and biological pathways involving the G3BP2 gene, a critical regulator of stress granule formation and cellular responses to stress. By employing CRISPR/Cas9 technology, these cell lines have been meticulously crafted to facilitate in-depth analysis of G3BP2’s role in various cellular processes, including mRNA metabolism, cellular signaling, and the cellular response to environmental stresses such as viral infections.
The primary function of G3BP2 is its involvement in the assembly of stress granules — cytoplasmic aggregates that play a vital role in regulating mRNA translation, stability, and degradation during stress conditions. By utilizing G3BP2 knockout cell lines, researchers can gain insights into the molecular mechanisms that underpin stress granule dynamics and their implications in diseases such as cancer, neurodegenerative disorders, and viral pathogenesis. These models are invaluable for elucidating the roles of G3BP2 in both physiological and pathological contexts.
In a competitive landscape of gene knockout technologies, G3BP2 Gene Knockout Cell Lines stand out due to their ease of use and reliability. Unlike other approaches that may lack specificity or have lower efficiency, these cell lines provide a robust tool for investigators seeking to conduct functional studies with precision. They allow for the reproducible and controlled examination of G3BP2’s functions while minimizing off-target effects commonly associated with other gene editing techniques.
For researchers and clinicians, the ability to study G3BP2's interactions in a controlled environment opens avenues for identifying novel therapeutic targets and developing strategies for drug discovery. The significance of these knockout models is further underscored by their potential applications in high-throughput screening for compounds that can modulate stress responses.
Our company specializes in the development and supply of cutting-edge biological products that advance life sciences research. With a commitment to quality and innovation, we are dedicated to supporting researchers in their quest to unlock the complexities of gene function and disease mechanisms. G3BP2 Gene Knockout Cell Lines represent an essential tool in this mission, empowering the scientific community to explore and address some of the most pressing questions in biology and medicine today.
Please note that all services are for research use only. Not intended for any clinical use.
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