Gene: FRMD5
Official Full Name: FERM domain containing 5provided by HGNC
Gene Summary: Enables integrin binding activity and protein kinase binding activity. Involved in negative regulation of cell motility; positive regulation of cell adhesion; and regulation of cell migration. Located in adherens junction. Implicated in neurodevelopmental disorder with eye movement abnormalities and ataxia. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24376 | FRMD5 Knockout cell line (HeLa) | Human | FRMD5 | 1:3~1:6 | Negative | Online Inquiry |
KO24377 | FRMD5 Knockout cell line (HCT 116) | Human | FRMD5 | 1:2~1:4 | Negative | Online Inquiry |
KO24378 | FRMD5 Knockout cell line (HEK293) | Human | FRMD5 | 1:3~1:6 | Negative | Online Inquiry |
KO24379 | FRMD5 Knockout cell line (A549) | Human | FRMD5 | 1:3~1:4 | Negative | Online Inquiry |
FRMD5 Gene Knockout Cell Lines are specially developed cellular models that enable researchers to study the functional roles of the FRMD5 gene by completely removing its expression in specific cell types. This genetic alteration provides a powerful tool for examining cellular mechanisms and pathways associated with this gene, particularly in the context of cancer, cellular signaling, and other physiological processes.
The key function of FRMD5 Gene Knockout Cell Lines lies in their ability to facilitate the elucidation of gene function. By utilizing CRISPR/Cas9 gene editing technology, these cell lines have undergone precise modifications that render the FRMD5 gene nonfunctional. This targeted approach allows for the observation of phenotypic changes and the assessment of downstream effects on cellular behavior, gene expression, and metabolic activities, helping to decode the gene's role in various biological processes.
Scientifically, these knockout cell lines are invaluable in both research and clinical settings. They enable advanced investigations into the biological pathways influenced by FRMD5, offering insights into its involvement in diseases such as cancer and developmental disorders. Additionally, these models assist in screening potential therapeutic agents, guiding the development of targeted drugs by revealing how FRMD5 knockout cells respond to treatment.
One of the unique selling points of our FRMD5 Gene Knockout Cell Lines is the meticulous quality control and validation they undergo, ensuring that the knockout efficiency is verified and that the resulting cell lines retain stable growth characteristics. Compared to traditional gene silencing methods, such as RNA interference, CRISPR-generated knockout models provide a more robust and permanent approach to gene disruption, leading to more reliable experimental outcomes.
For researchers and clinicians, the accessibility and specificity of these cell lines make them a valuable resource for advancing our understanding of gene function and its implications in health and disease. The ability to manipulate the FRMD5 gene’s expression provides novel insights into therapeutic strategies, positioning FRMD5 Gene Knockout Cell Lines as an essential component in the modern biological research toolkit.
Our company possesses extensive expertise in the development of genetically engineered cell lines, backed by a commitment to quality and innovation. We strive to support the scientific community by providing high-quality biological research tools that facilitate groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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