Gene: FRMD4B
Official Full Name: FERM domain containing 4Bprovided by HGNC
Gene Summary: This gene encodes a GRP1-binding protein which contains a FERM protein interaction domain as well as two coiled coil domains. This protein may play a role as a scaffolding protein. [provided by RefSeq, Mar 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29797 | FRMD4B Knockout cell line (HEK293) | Human | FRMD4B | 1:3~1:6 | Negative | Online Inquiry |
KO29798 | FRMD4B Knockout cell line (A549) | Human | FRMD4B | 1:3~1:4 | Negative | Online Inquiry |
FRMD4B Gene Knockout Cell Lines are engineered cellular models that have undergone precise genetic modification to inactivate the FRMD4B gene, a key player in various cellular signaling pathways. This innovative tool offers researchers a unique platform to study the gene's biological roles and its implications in disease mechanisms, particularly in cancer and neurodegenerative disorders.
The primary function of FRMD4B Gene Knockout Cell Lines revolves around elucidating the gene's contributions to cell proliferation, differentiation, and apoptosis. By utilizing CRISPR/Cas9 technology, the knockout process eliminates the expression of the FRMD4B protein, enabling scientists to investigate the subsequent phenotypic changes and alterations in cellular signaling cascades. This mechanism allows for a clearer understanding of the gene's potential as a therapeutic target, providing crucial insights into disease biomarkers and treatment strategies.
From a scientific standpoint, these cell lines are invaluable in both research and clinical applications. They provide a robust model for preclinical studies aimed at identifying biological pathways mediated by FRMD4B, facilitating the development of targeted therapies. Additionally, their utility in drug screening platforms enhances drug discovery processes by allowing for the assessment of compound efficacy against genetically defined backgrounds.
Compared to alternative models, such as wild-type cell lines, the FRMD4B Gene Knockout Cell Lines offer unparalleled specificity and relevance. Researchers can achieve greater confidence in their findings, as these lines eliminate confounding variables associated with gene expression. Moreover, the adaptability of these cell lines to various culture conditions makes them suitable for a range of experimental designs.
The FRMD4B Gene Knockout Cell Lines are an essential resource for researchers and clinicians seeking to deepen their understanding of FRMD4B-related biological processes and to explore novel therapeutic avenues. With our company's dedication to advancing genetic research, we provide high-quality, rigorously validated cell lines that empower the scientific community to drive innovation and discovery in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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