Gene: FOXP4
Official Full Name: forkhead box P4provided by HGNC
Gene Summary: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30553 | FOXP4 Knockout cell line (HeLa) | Human | FOXP4 | 1:3~1:6 | Negative | Online Inquiry |
KO30554 | FOXP4 Knockout cell line (HCT 116) | Human | FOXP4 | 1:2~1:4 | Negative | Online Inquiry |
KO30555 | FOXP4 Knockout cell line (HEK293) | Human | FOXP4 | 1:3~1:6 | Negative | Online Inquiry |
KO30556 | FOXP4 Knockout cell line (A549) | Human | FOXP4 | 1:3~1:4 | Negative | Online Inquiry |
FOXP4 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to eliminate the expression of the FOXP4 gene, which plays a pivotal role in various biological processes, including immune response and regulation of cell differentiation. By utilizing CRISPR-Cas9 technology, these cell lines provide a powerful tool for researchers to study the functional consequences of FOXP4 loss in different cellular contexts.
The primary function of FOXP4 Gene Knockout Cell Lines is to facilitate the investigation of the regulatory pathways and biological mechanisms mediated by the FOXP4 gene. Given FOXP4’s involvement in processes such as T-cell regulation and neuronal differentiation, the knockout models enable scientists to dissect these complex interactions in a controlled environment. Researchers can observe how the absence of FOXP4 influences cell behavior, gene expression profiles, and response to external stimuli, contributing to a better understanding of diseases associated with this genetic alteration.
The scientific importance of these cell lines extends to both fundamental research and clinical applications, such as exploring therapeutic targets for autoimmune diseases and cancers where FOXP4 is implicated. These models allow for the assessment of potential drug responses and the identification of novel biomarkers, making them invaluable for translational research.
Unique to our offering, FOXP4 Gene Knockout Cell Lines are thoroughly validated for gene editing efficiency, ensuring high specificity and minimal off-target effects. This precision in genetic manipulation dramatically enhances experimental reliability and reproducibility, setting them apart from conventional knockout models which may exhibit variable results. Furthermore, our product comes with comprehensive technical support and detailed characterization data, empowering researchers to maximize their experimental outcomes.
In conclusion, the FOXP4 Gene Knockout Cell Lines are essential for advancing our understanding of gene function and disease mechanisms, presenting significant value to researchers and clinicians alike. Our company's expertise in genetic engineering and commitment to quality ensure that you receive a product that meets the highest scientific standards, enabling groundbreaking discoveries in the field of molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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