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FOXN3 Knockout Cell Lines

Gene: FOXN3

Official Full Name: forkhead box N3provided by HGNC

Gene Summary: This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06580 FOXN3 Knockout cell line (HeLa) Human FOXN3 1:3~1:6 Negative Online Inquiry
KO06581 FOXN3 Knockout cell line (HCT 116) Human FOXN3 1:2~1:4 Negative Online Inquiry
KO06582 FOXN3 Knockout cell line (HEK293) Human FOXN3 1:3~1:6 Negative Online Inquiry
KO06583 FOXN3 Knockout cell line (A549) Human FOXN3 1:3~1:4 Negative Online Inquiry

Background

FOXN3 Gene Knockout Cell Lines are genetically modified cell lines in which the FOXN3 gene has been selectively disrupted, allowing researchers to study the functional implications of this critical gene in various biological processes. FOXN3 is a member of the forkhead box (FOX) family of transcription factors and plays a key role in regulating immune responses, cellular differentiation, and development.

The mechanism underlying these knockout cell lines involves CRISPR-Cas9 technology, which facilitates targeted editing of the genomic DNA. By disabling the FOXN3 gene, scientists can elucidate its role in processes such as T-cell development and regulation, potentially unveiling its contributions to autoimmune diseases and cancer immunotherapy. Researchers can use these cell lines to investigate signaling pathways, gene interactions, and cellular responses, thereby enabling a comprehensive understanding of immune system dynamics.

The scientific importance of FOXN3 Gene Knockout Cell Lines is underscored by their applications in both research and clinical settings. These cell lines provide a robust platform for drug screening, functional genomics studies, and the development of therapeutic interventions aimed at modulating immune responses or correcting dysregulation linked to health disorders. They are particularly valuable for studying specific phenotypic alterations caused by the loss of FOXN3 function, paving the way for enhanced clinical strategies.

What sets FOXN3 Gene Knockout Cell Lines apart from other gene-editing models is their high fidelity and reproducibility, making them ideal for long-term studies. Additionally, these cell lines are fully characterized, with thorough validation ensuring consistent performance in experimental settings. This reliability positions them as a premier choice for academic and commercial laboratories alike.

For researchers and clinicians invested in the realms of immunology and gene regulation, FOXN3 Gene Knockout Cell Lines represent not just a research tool but a gateway to innovative insights and advancements. Our company, a leader in the field of genetic engineering and cell-line development, is committed to providing high-quality biological products that empower scientific discovery and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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