Gene: FOXK1
Official Full Name: forkhead box K1provided by HGNC
Gene Summary: Enables 14-3-3 protein binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and transcription cis-regulatory region binding activity. Involved in several processes, including intracellular glucose homeostasis; negative regulation of autophagy; and regulation of DNA-templated transcription. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09770 | FOXK1 Knockout cell line (HeLa) | Human | FOXK1 | 1:3~1:6 | Negative | Online Inquiry |
KO09771 | FOXK1 Knockout cell line (HCT 116) | Human | FOXK1 | 1:2~1:4 | Negative | Online Inquiry |
KO09772 | FOXK1 Knockout cell line (HEK293) | Human | FOXK1 | 1:3~1:6 | Negative | Online Inquiry |
KO09773 | FOXK1 Knockout cell line (A549) | Human | FOXK1 | 1:3~1:4 | Negative | Online Inquiry |
FOXK1 Gene Knockout Cell Lines are genetically engineered cell models designed to study the functional implications of the FOXK1 gene, a crucial regulator of cellular processes such as growth, differentiation, and response to stress. Utilizing innovative CRISPR-Cas9 technology, these knockout cell lines facilitate precise editing of the FOXK1 gene, enabling researchers to observe the resultant cellular phenotypes and alterations in metabolic pathways.
The primary mechanism of action involves the targeted disruption of the FOXK1 gene, leading to the loss of its regulatory function. This knockout model provides researchers with the ability to pinpoint FOXK1's role in various biological processes, including cellular proliferation and apoptosis. Studying these cell lines allows for the examination of conditions related to cancer, developmental anomalies, and metabolic disorders, thus contributing crucial insights into disease mechanisms.
The scientific significance of FOXK1 Gene Knockout Cell Lines extends to both research and clinical settings. Their application in academic laboratories can illuminate gene function and protein interactions, while also holding potential for therapeutic explorations, such as drug development and biomarker identification. Compared to traditional cell lines, these knockout models present an unparalleled approach to understanding gene function due to their specificity and the ability to eliminate interference from the endogenous FOXK1 protein.
What sets our FOXK1 Gene Knockout Cell Lines apart is not only the precision of the knockout but also the accompanying validation data, which confirms successful gene modification and the stability of the altered cellular characteristics. This reliability is essential for researchers seeking reproducible results in their experiments.
In essence, FOXK1 Gene Knockout Cell Lines are invaluable resources for scientists aiming to delve into the complexities of gene functions and disease processes. With our company’s commitment to quality and innovation in biological products, we are dedicated to supporting the scientific community with advanced tools that facilitate groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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