Gene: FNDC3A
Official Full Name: fibronectin type III domain containing 3Aprovided by HGNC
Gene Summary: Enables RNA binding activity. Predicted to be involved in spermatid development. Predicted to act upstream of or within Sertoli cell development; cell-cell adhesion; and fertilization. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30252 | FNDC3A Knockout cell line (HeLa) | Human | FNDC3A | 1:3~1:6 | Negative | Online Inquiry |
KO30253 | FNDC3A Knockout cell line (HCT 116) | Human | FNDC3A | 1:2~1:4 | Negative | Online Inquiry |
KO30254 | FNDC3A Knockout cell line (HEK293) | Human | FNDC3A | 1:3~1:6 | Negative | Online Inquiry |
KO30255 | FNDC3A Knockout cell line (A549) | Human | FNDC3A | 1:3~1:4 | Negative | Online Inquiry |
FNDC3A Gene Knockout Cell Lines are genetically modified cellular systems designed to specifically disable the FNDC3A gene, which plays a pivotal role in various biological processes including cellular metabolism and muscle function. These cell lines utilize the CRISPR-Cas9 gene editing technology to create precise knockouts, enabling researchers to investigate the gene's function and its implications in health and disease mechanisms.
The primary function of FNDC3A Gene Knockout Cell Lines is to provide a robust model for studying the loss-of-function phenotypes associated with FNDC3A. By observing the cellular changes that occur when this gene is inactive, researchers can gain insights into the underlying biological pathways and physiological consequences, particularly in metabolic disorders and muscle disorders. The mechanism behind this product leverages CRISPR-Cas9's efficiency in inducing double-strand breaks in the DNA, leading to insertions or deletions that result in gene silencing.
The scientific importance of FNDC3A Gene Knockout Cell Lines lies in their applications across multiple research fields, including regenerative medicine, metabolic research, and cancer biology. Clinically, understanding FNDC3A's role can lead to innovative therapeutic strategies aimed at treating conditions linked to its dysfunction. These cell lines serve as a crucial tool in drug discovery and development, aiding in the identification of potential drug targets and the effects of therapeutics on cellular behavior.
Unique selling points of FNDC3A Gene Knockout Cell Lines include their high specificity and reproducibility, minimal off-target effects, and the capability to be used in high-throughput screening assays. Compared to traditional gene modification methods like RNA interference, these knockout lines provide stable gene silencing and the opportunity to study long-term effects on cellular physiology.
For researchers, clinicians, and biopharmaceutical companies, FNDC3A Gene Knockout Cell Lines represent an invaluable asset in advancing scientific knowledge and therapeutic innovations. With a commitment to excellence in genetic engineering technologies, our company is dedicated to providing top-tier biological products that empower scientific discovery and drive improvements in human health.
Please note that all services are for research use only. Not intended for any clinical use.
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