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FNBP1 Knockout Cell Lines

Gene: FNBP1

Official Full Name: formin binding protein 1provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29957 FNBP1 Knockout cell line (HeLa) Human FNBP1 1:3~1:6 Negative Online Inquiry
KO29958 FNBP1 Knockout cell line (HCT 116) Human FNBP1 1:2~1:4 Negative Online Inquiry
KO29959 FNBP1 Knockout cell line (HEK293) Human FNBP1 1:3~1:6 Negative Online Inquiry
KO29960 FNBP1 Knockout cell line (A549) Human FNBP1 1:3~1:4 Negative Online Inquiry

Background

FNBP1 Gene Knockout Cell Lines are genetically engineered cells that have had the FNBP1 gene selectively inactivated, thereby providing a valuable tool for studying the biological implications of FNBP1 in various cellular contexts. FNBP1, or Formin-binding protein 1, is an important cytoskeletal regulator involved in actin filament dynamics, cell motility, and cellular signaling pathways. By knocking out this gene, researchers can observe the resultant phenotypic changes and elucidate the roles that FNBP1 plays in processes such as migration, proliferation, and response to stimuli.

These cell lines function as a model to investigate the mechanisms through which FNBP1 influences cellular behavior and interacts with other proteins within actin-associated pathways. In essence, the absence of FNBP1 enables the study of actin cytoskeleton remodeling and its implications in various diseases, including cancer metastasis and neurodegenerative disorders. Research utilizing FNBP1 knockout cell lines can lead to insights that drive therapeutic development, as they mimic the biological environment in human tissues more accurately than traditional models.

The scientific importance of FNBP1 Gene Knockout Cell Lines lies in their myriad of applications across research and clinical settings. They are instrumental in dissecting the mechanistic details of disease states influenced by cytoskeletal abnormalities, making them invaluable for researchers seeking to develop new treatments or investigate disease pathways.

What sets our FNBP1 Gene Knockout Cell Lines apart from alternatives is their verified specificity and validated phenotypic profiles, ensuring reliable and reproducible results. Additionally, our cell lines come with supporting data that facilitate user experiments, enhancing experimental efficiency and reducing validation time.

Researchers and clinicians will find these cell lines indispensable for advancing their understanding of actin dynamics and exploring new therapeutic targets in disease states. Our company prides itself on cutting-edge genetic engineering techniques and robust validation systems, ensuring that our biological products meet the highest standards of excellence in research innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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