Gene: FN3KRP
Official Full Name: fructosamine 3 kinase related proteinprovided by HGNC
Gene Summary: A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17572 | FN3KRP Knockout cell line (HeLa) | Human | FN3KRP | 1:3~1:6 | Negative | Online Inquiry |
KO17573 | FN3KRP Knockout cell line (HCT 116) | Human | FN3KRP | 1:2~1:4 | Negative | Online Inquiry |
KO17574 | FN3KRP Knockout cell line (HEK293) | Human | FN3KRP | 1:3~1:6 | Negative | Online Inquiry |
KO17575 | FN3KRP Knockout cell line (A549) | Human | FN3KRP | 1:3~1:4 | Negative | Online Inquiry |
FN3KRP Gene Knockout Cell Lines represent a pivotal advancement in genetic research, providing invaluable tools for studying the functional roles of the FN3KRP gene within various biological contexts. These cell lines are generated through precise gene-editing techniques, such as CRISPR/Cas9, enabling the targeted disruption of FN3KRP, which encodes for a protein involved in critical cellular processes, including post-translational modifications and cellular stress response mechanisms.
The primary function of FN3KRP knockout cell lines is to facilitate the exploration of the gene's contributions to metabolic pathways, cell signaling, and phenotypic characteristics. By systematically observing the effects of the gene's absence, researchers can delineate its roles in cellular behavior, survival, and adaptation under stress conditions. This has significant implications for understanding diseases linked to metabolic dysregulation and cellular stress responses, including cancer and neurodegenerative conditions.
In clinical and research settings, the applications of FN3KRP gene knockout cell lines are extensive. They serve as vital models for drug testing, biomarker discovery, and the mechanistic dissection of FN3KRP’s involvement in cellular dysfunction. Additionally, they are ideal for collaborative studies that aim to decipher gene-environment interactions in health and disease.
Compared to conventional knockout models, these FN3KRP gene knockout cell lines offer several advantages, including enhanced specificity, reproducibility, and the ability to study gene function across diverse cell types. Their optimized design allows for greater ease of use in experimental setups, significantly saving time and resources for researchers.
For researchers and clinicians eager to deepen their understanding of genetic contributions to disease, FN3KRP gene knockout cell lines provide a robust and reliable platform. The ability to manipulate and analyze the FN3KRP gene opens doors to innovative therapeutic strategies and insights into human health.
Our company, with a commitment to advancing biotechnology, specializes in the development of cutting-edge genetic tools. With our expertise in cell line generation and gene editing technologies, we are dedicated to empowering scientific discovery and fostering advancements in the field of genetic research.
Please note that all services are for research use only. Not intended for any clinical use.
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