Gene: FMNL3
Official Full Name: formin like 3provided by HGNC
Gene Summary: The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23584 | FMNL3 Knockout cell line (HeLa) | Human | FMNL3 | 1:3~1:6 | Negative | Online Inquiry |
KO23585 | FMNL3 Knockout cell line (HCT 116) | Human | FMNL3 | 1:2~1:4 | Negative | Online Inquiry |
KO23586 | FMNL3 Knockout cell line (HEK293) | Human | FMNL3 | 1:3~1:6 | Negative | Online Inquiry |
KO23587 | FMNL3 Knockout cell line (A549) | Human | FMNL3 | 1:3~1:4 | Negative | Online Inquiry |
FMNL3 Gene Knockout Cell Lines are specially engineered cellular models that lack the functional FMNL3 gene, which encodes an actin-nucleating protein implicated in various cellular processes, including cell migration, proliferation, and cytoskeletal dynamics. These cell lines are invaluable tools for researchers aiming to investigate the role of FMNL3 in cellular behavior and its association with diseases such as cancer and neurodegeneration. By creating a specific knockout of the FMNL3 gene, scientists can dissect the signaling pathways and molecular mechanisms through which this protein operates, providing deeper insights into its contributions to cellular physiology.
The primary function of the FMNL3 gene knockout cell lines lies in their ability to model the absence of FMNL3 activity, allowing for the precise evaluation of changes in cell morphology, migration patterns, and other functional assays. This enables researchers to elucidate the downstream effects of FMNL3 loss and how it may influence tumor metastasis or neuronal function, thereby opening avenues for therapeutic interventions.
In terms of scientific importance, these knockout cell lines are crucial for validating hypotheses related to FMNL3 in a controlled environment, enabling high-throughput screening for drug candidates targeting cytoskeletal interactions. In clinical research applications, these models can facilitate the study of potential biomarkers for diseases associated with FMNL3 dysregulation, leading to improved diagnostic or therapeutic strategies.
The unique selling points of our FMNL3 Gene Knockout Cell Lines include their high specificity and reproducibility, paired with rigorous quality control measures that ensure optimal performance in various experimental conditions. Compared to alternatives, these cell lines provide a unique opportunity for precise genetic manipulation without the concerns of off-target effects commonly associated with other knockout techniques.
For researchers and clinicians, the FMNL3 Gene Knockout Cell Lines represent an essential tool that offers clarity in experimental design and results, driving forward the understanding of the complexities of cellular behavior. Leveraging our expertise in genetic engineering and cell line development, our company is committed to providing high-quality biological products that empower cutting-edge research and therapeutic discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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