Gene: FLOT1
Official Full Name: flotillin 1provided by HGNC
Gene Summary: This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03077 | FLOT1 Knockout cell line (HeLa) | Human | FLOT1 | 1:3~1:6 | Negative | Online Inquiry |
KO03078 | FLOT1 Knockout cell line (HCT 116) | Human | FLOT1 | 1:2~1:4 | Negative | Online Inquiry |
KO03079 | FLOT1 Knockout cell line (HEK293) | Human | FLOT1 | 1:3~1:6 | Negative | Online Inquiry |
KO03080 | FLOT1 Knockout cell line (A549) | Human | FLOT1 | 1:3~1:4 | Negative | Online Inquiry |
FLOT1 Gene Knockout Cell Lines represent a significant advancement in cellular biology, providing researchers with invaluable tools for investigating the role of the FLOT1 gene in various physiological and pathological processes. FLOT1, known for its involvement in the formation of lipid rafts and endocytosis, plays a critical role in cellular signal transduction and membrane dynamics. These knockout cell lines have been meticulously engineered to disable the FLOT1 gene, allowing for comprehensive analysis of its functional contributions in a controlled environment.
The fundamental mechanism of the FLOT1 knockout cell lines involves targeted gene editing techniques, such as CRISPR/Cas9, which result in the permanent omission of the FLOT1 gene. This disruption permits researchers to examine the subsequent cellular responses and compensatory mechanisms that may arise from the absence of FLOT1, including alterations in vesicular transport, cell signaling pathways, and overall cellular morphology. Such insights are essential for advancing our understanding of cellular processes and their implications in diseases such as cancer, neurodegeneration, and infectious diseases.
The scientific importance of FLOT1 Gene Knockout Cell Lines lies in their versatile applications in both research and clinical contexts. They serve as critical models in drug development and pathophysiological studies, enabling scientists to investigate potential therapeutic targets and molecular interactions. Moreover, these cell lines offer a reliable system for screening pharmaceuticals that may modulate the pathways influenced by FLOT1.
Compared to alternative cell lines, the unique aspect of FLOT1 Gene Knockout Cell Lines is the specificity and reliability of gene disruption, allowing for clear attribution of observed effects directly to the absence of the FLOT1 gene. This level of precision minimizes off-target effects that can confound results, providing a clearer understanding of cellular dynamics.
For researchers, clinicians, and biopharmaceutical companies aiming to unravel intricate cellular mechanisms, the FLOT1 Gene Knockout Cell Lines represent a robust and scalable resource for advancing scientific discovery and therapeutic innovation. Our company's expertise in developing high-quality biological products ensures that you will receive not only a superior product but also ongoing support in your research endeavors, fostering the next leap forward in cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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