Gene: FKBP10
Official Full Name: FKBP prolyl isomerase 10provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.[provided by RefSeq, Nov 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00785 | FKBP10 Knockout cell line(HT-29) | Human | FKBP10 | 1:2~1:4 | Negative | Online Inquiry |
KO17587 | FKBP10 Knockout cell line (HeLa) | Human | FKBP10 | 1:3~1:6 | Negative | Online Inquiry |
KO17588 | FKBP10 Knockout cell line (HCT 116) | Human | FKBP10 | 1:2~1:4 | Negative | Online Inquiry |
KO17589 | FKBP10 Knockout cell line (HEK293) | Human | FKBP10 | 1:3~1:6 | Negative | Online Inquiry |
KO17590 | FKBP10 Knockout cell line (A549) | Human | FKBP10 | 1:3~1:4 | Negative | Online Inquiry |
FKBP10 Gene Knockout Cell Lines represent a cutting-edge, genetically modified tool utilized in biological research, specifically designed to elucidate the functional roles of the FKBP10 gene. This gene encodes a protein that acts as a peptidyl-prolyl isomerase, influencing protein folding and stability. By employing advanced CRISPR-Cas9 technology, these knockout cell lines effectively disable the FKBP10 gene, facilitating in-depth studies into its contributions to cellular processes and its implication in various disease states, including fibrosis and certain cancers.
The primary function of FKBP10 Gene Knockout Cell Lines is to serve as a model system that allows researchers to assess the phenotypic and molecular consequences of FKBP10 loss. Through comparative analyses with wild-type cell lines, scientists can investigate changes in cellular pathways, signaling mechanisms, and gene expression profiles. This functionality is critical in research settings, enabling a deeper understanding of the gene's regulatory roles and its potential as a therapeutic target.
The scientific importance of these knockout cell lines extends to both fundamental and applied research. They are invaluable in the investigation of disease mechanisms and drug responses, providing a robust platform for developing novel therapeutic strategies. In clinical settings, these cell lines can facilitate the screening of drugs that may ameliorate diseases associated with FKBP10 dysregulation.
Compared to traditional gene knockdown methods, FKBP10 Gene Knockout Cell Lines offer enhanced specificity and robustness in gene modulation. The CRISPR-Cas9 technology employed ensures high efficiency and accuracy in gene disruption, which can significantly reduce off-target effects typically associated with RNA interference methods. This precision not only elevates the reliability of experimental outcomes but also enhances the reproducibility of research findings.
For researchers, clinicians, and biopharmaceutical professionals, utilizing FKBP10 Gene Knockout Cell Lines translates to a leap forward in understanding and manipulating cellular functions. The ability to explore gene function with such precision allows for better-informed research efforts and potentially accelerates the development of effective therapies.
Our company prides itself on its commitment to advancing biotechnological solutions. With extensive expertise in genetic engineering and cell line development, we provide high-quality, reliable tools like FKBP10 Gene Knockout Cell Lines that empower the scientific community to push the boundaries of discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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