Gene: FBXO30
Official Full Name: F-box protein 30provided by HGNC
Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25200 | FBXO30 Knockout cell line (HeLa) | Human | FBXO30 | 1:3~1:6 | Negative | Online Inquiry |
KO25201 | FBXO30 Knockout cell line (HCT 116) | Human | FBXO30 | 1:2~1:4 | Negative | Online Inquiry |
KO25202 | FBXO30 Knockout cell line (HEK293) | Human | FBXO30 | 1:3~1:6 | Negative | Online Inquiry |
KO25203 | FBXO30 Knockout cell line (A549) | Human | FBXO30 | 1:3~1:4 | Negative | Online Inquiry |
FBXO30 Gene Knockout Cell Lines are genetically engineered cell cultures designed to disable the function of the FBXO30 gene, which encodes a member of the F-box protein family involved in ubiquitin-mediated protein degradation. The knockout of this gene is achieved through cutting-edge CRISPR/Cas9 technology, allowing researchers to examine the physiological and molecular implications of FBXO30 loss. These cell lines serve as invaluable tools for studying the role of the FBXO30 gene in various biological processes, including cell cycle regulation, signal transduction pathways, and tumorigenesis.
The primary function of FBXO30 is to facilitate the ubiquitination of target proteins, modulating their stability and function within the cell. By utilizing these knockout cell lines, researchers can effectively elucidate the downstream effects of FBXO30 loss, thereby gaining insights into cellular processes that contribute to cancer progression and other diseases. The scientific importance of these cell lines is amplified by their applicability in both basic research and translational studies, allowing for the development of novel therapeutic strategies targeting pathways affected by FBXO30 dysfunction.
One of the unique advantages of our FBXO30 Gene Knockout Cell Lines is their high specificity and reliability, which surpasses traditional methods that may inadvertently affect other genes or pathways. This specificity allows for clearer interpretation of experimental results, reducing confounding factors in data analysis. Furthermore, these cell lines are rigorously validated to ensure consistent performance across experiments, making them an essential resource for both academic and clinical research environments.
Researchers and clinicians will find considerable value in utilizing these cell lines for drug discovery, biomarker development, and understanding disease mechanisms. The precision and efficiency offered by the FBXO30 knockouts enable the rapid advancement of knowledge in the field of genetics and cell biology, thereby facilitating innovation in therapeutic interventions.
At [Your Company Name], we pride ourselves on being at the forefront of biogenetic advancements, providing high-quality, reliable products that empower the scientific community. Our expertise in gene editing technology ensures that our FBXO30 Gene Knockout Cell Lines are not only effective but also contribute to transformative research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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