Gene: FARP2
Official Full Name: FERM, ARH/RhoGEF and pleckstrin domain protein 2provided by HGNC
Gene Summary: Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within Rac protein signal transduction and neuron remodeling. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08683 | FARP2 Knockout cell line (HeLa) | Human | FARP2 | 1:3~1:6 | Negative | Online Inquiry |
KO08684 | FARP2 Knockout cell line (HCT 116) | Human | FARP2 | 1:2~1:4 | Negative | Online Inquiry |
KO08685 | FARP2 Knockout cell line (HEK293) | Human | FARP2 | 1:3~1:6 | Negative | Online Inquiry |
KO08686 | FARP2 Knockout cell line (A549) | Human | FARP2 | 1:3~1:4 | Negative | Online Inquiry |
FARP2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the FARP2 gene, a crucial component implicated in signaling pathways that regulate cellular processes such as proliferation, differentiation, and apoptosis. These knockout cell lines enable researchers to study the functional consequences of FARP2 deficiency, providing insights into its role in various biological contexts, including cancer and neurobiology.
The primary mechanism at work in FARP2 gene knockout cell lines involves targeted gene disruption, achieved through CRISPR/Cas9 technology or similar genome-editing methodologies. This precise alteration allows for the observation of changes in cellular behavior and signaling pathways that arise from the absence of FARP2. Researchers can utilize these cell lines to dissect the molecular mechanisms associated with FARP2 and its involvement in certain diseases, thereby elucidating potential therapeutic targets.
The scientific importance of FARP2 gene knockout cell lines is underscored by their applications in both academic and clinical research settings. These tools are invaluable in studying diseases where FARP2 plays a pivotal role, allowing for the development of innovative treatment strategies. Moreover, they can be employed in drug discovery processes to screen for compounds that modulate pathways influenced by FARP2.
Compared to alternative methods, such as transient knockdown techniques or overexpression systems, FARP2 knockout cell lines offer several advantages. This includes stable genetic modification, resulting in consistent cellular behavior over time, and the ability to study long-term effects of gene loss. Their use can significantly enhance the robustness and reproducibility of experimental findings.
Researchers and clinicians can benefit greatly from these cell lines, as they provide a more accurate model for investigating gene function and disease mechanisms. By utilizing FARP2 gene knockout cell lines, users can contribute to the advancement of biomedical research that seeks to tackle critical health challenges.
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Please note that all services are for research use only. Not intended for any clinical use.
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