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FAM83H Knockout Cell Lines

Gene: FAM83H

Official Full Name: family with sequence similarity 83 member Hprovided by HGNC

Gene Summary: The protein encoded by this gene plays an important role in the structural development and calcification of tooth enamel. Defects in this gene are a cause of amelogenesis imperfecta type 3 (AI3). [provided by RefSeq, Mar 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17827 FAM83H Knockout cell line (HeLa) Human FAM83H 1:3~1:6 Negative Online Inquiry
KO17828 FAM83H Knockout cell line (HCT 116) Human FAM83H 1:2~1:4 Negative Online Inquiry
KO17829 FAM83H Knockout cell line (A549) Human FAM83H 1:3~1:4 Negative Online Inquiry

Background

The FAM83H Gene Knockout Cell Lines are specialized cellular models created to study the functional roles and biological implications of the FAM83H gene through targeted gene disruption techniques. These knockout cell lines provide researchers an invaluable tool to explore the gene's involvement in various biological processes and its potential link to diseases, particularly in cancer biology and cellular differentiation.

FAM83H is recognized for its role in the Wnt signaling pathway and its contributions to the regulation of cellular proliferation and survival. The knockout of this gene leads to significant alterations in cellular behavior, allowing for the elucidation of FAM83H's functions through comparative analyses with wild-type cells. This gene disruption is typically facilitated by CRISPR-Cas9 technology, which introduces precise alterations in the genomic DNA, creating stable cell lines that maintain the knockout phenotype over successive passages.

The scientific value of FAM83H Gene Knockout Cell Lines lies in their application in both basic and translational research. These cell lines enable the investigation of FAM83H's role in oncogenic processes, offering insights into potential therapeutic targets for cancer treatment. Additionally, they can facilitate the identification of downstream effectors and help elucidate the molecular mechanisms underpinning various signaling pathways.

What sets these knockout cell lines apart from alternatives is their rigorously validated gene knockout efficiency and phenotypic stability, which provide reliable data for experimental results. They also come with comprehensive characterization data to help researchers understand the impact of FAM83H loss on cellular function, providing a clear advantage for those requiring precision in their studies.

Researchers and clinicians seeking to deepen their understanding of genetic influences on cellular dynamics will find significant value in the FAM83H Gene Knockout Cell Lines. With enhanced reproducibility and the potential for groundbreaking discoveries in cellular biology, these models will empower users to conduct high-impact research. Our company’s dedication to providing high-quality biological products, reinforced by a team of experts grounded in molecular biology and genetics, ensures that you receive the best tools available to enhance your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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