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FAAP100 Knockout Cell Lines

Gene: FAAP100

Official Full Name: FA core complex associated protein 100provided by HGNC

Gene Summary: FAAP100 is a component of the Fanconi anemia (FA; MIM 277650) core complex and is required for core complex stability and FANCD2 (see MIM 227646) monoubiquitination (Ling et al., 2007 [PubMed 17396147]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26100 FAAP100 Knockout cell line (HeLa) Human FAAP100 1:3~1:6 Negative Online Inquiry
KO26101 FAAP100 Knockout cell line (HCT 116) Human FAAP100 1:2~1:4 Negative Online Inquiry
KO26102 FAAP100 Knockout cell line (HEK293) Human FAAP100 1:3~1:6 Negative Online Inquiry
KO26103 FAAP100 Knockout cell line (A549) Human FAAP100 1:3~1:4 Negative Online Inquiry

Background

FAAP100 Gene Knockout Cell Lines are precisely engineered cellular models that enable researchers to investigate the functional roles of the FAAP100 gene in various biological processes. These cell lines are designed using advanced CRISPR/Cas9 technology to create precise deletions in the FAAP100 gene, leading to the disruption of its normal activity. By doing so, these knockout cell lines provide a powerful tool for functional genomics, allowing scientists to elucidate gene pathways, assess cellular responses, and understand the molecular mechanisms underlying diseases.

The primary function of FAAP100 Gene Knockout Cell Lines is to facilitate the study of FAAP100's role in DNA repair processes and its implications in genomic stability. The absence of FAAP100 leads to alterations in cellular behavior, thus serving as a valuable system for exploring the correlation between FAAP100 depletion and phenotypic outcomes such as increased susceptibility to DNA damage. This gives researchers insights into cancer biology, where disruptions in DNA repair pathways are often implicated.

In the realm of clinical research, these knockout cell lines hold significant importance in the development of targeted therapies and personalized medicine. They provide a robust means of screening potential drug candidates and exploring therapeutic strategies that target specific genetic alterations, thereby enhancing treatment efficacy.

Compared to standard cell models, FAAP100 Gene Knockout Cell Lines offer unparalleled specificity and reliability, as they accurately mimic the genetic alterations found in various pathological conditions. This precision makes them more predictive of in vivo responses, enabling researchers to make more informed conclusions.

For researchers and clinicians committed to advancing their understanding of gene function and disease mechanisms, the FAAP100 Gene Knockout Cell Lines represent an invaluable resource. Their unique capability to contribute to novel therapeutic discoveries and improve translational outcomes underscores their significance in modern biological research.

With a commitment to innovation and quality, our company specializes in providing cutting-edge biological products that empower researchers to push the boundaries of scientific knowledge. Our expertise ensures that each product, including the FAAP100 Gene Knockout Cell Lines, meets rigorous standards of reliability and effectiveness, supporting your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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