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EXD3 Knockout Cell Lines

Gene: EXD3

Official Full Name: exonuclease 3'-5' domain containing 3provided by HGNC

Gene Summary: Predicted to enable 3'-5' exonuclease activity; metal ion binding activity; and nucleic acid binding activity. Predicted to be involved in nucleobase-containing compound metabolic process. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17858 EXD3 Knockout cell line (HeLa) Human EXD3 1:3~1:6 Negative Online Inquiry
KO17859 EXD3 Knockout cell line (HCT 116) Human EXD3 1:2~1:4 Negative Online Inquiry
KO17860 EXD3 Knockout cell line (HEK293) Human EXD3 1:3~1:6 Negative Online Inquiry
KO17861 EXD3 Knockout cell line (A549) Human EXD3 1:3~1:4 Negative Online Inquiry

Background

EXD3 Gene Knockout Cell Lines are a specialized series of cell lines engineered to exhibit a complete knockout of the EXD3 gene, a crucial component involved in DNA repair mechanisms. These cell lines have undergone precise CRISPR/Cas9 gene-editing technology to ensure the targeted disruption of EXD3, allowing researchers to further unravel the gene's role in cellular processes such as DNA repair, replication, and response to oxidative stress.

The primary function of EXD3 encompasses its involvement in the repair of damaged DNA, which is fundamental to maintaining genomic stability. By utilizing these knockout cell lines, researchers can investigate the downstream effects of EXD3 ablation on cellular viability, proliferation, and the intricate pathways that engage when DNA repair is compromised. This provides insights into broader biological processes, including those leading to oncogenesis, making the cell lines invaluable in cancer research and other disease models.

The scientific relevance of EXD3 Gene Knockout Cell Lines extends into both academic and clinical research settings. Their applicability in drug discovery and efficacy studies, particularly in identifying novel chemotherapeutic agents that target DNA repair pathways, highlights a crucial application area. Additionally, these cell lines serve as a powerful tool for studying cellular responses to various genotoxic stresses, enabling a deeper understanding of disease mechanisms.

Compared to other cell lines available on the market, the EXD3 Gene Knockout Cell Lines offer a unique, highly specific model system that allows for precise genetic manipulation and highly reproducible results, ensuring that researchers can conduct clearer and more targeted experiments. Moreover, they contribute to advancing personalized medicine approaches, as understanding gene functionality can lead to more tailored therapeutic strategies.

In summary, EXD3 Gene Knockout Cell Lines represent a cutting-edge resource for researchers and clinicians interested in the complexities of DNA repair and its implications in human health. Developed by a team of experts in genetic engineering and cell biology, our company stands out in delivering high-quality biological products that are essential for modern scientific inquiry and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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