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EVI5 Knockout Cell Lines

Gene: EVI5

Official Full Name: ecotropic viral integration site 5provided by HGNC

Gene Summary: Enables GTPase activator activity and small GTPase binding activity. Involved in positive regulation of GTPase activity and retrograde transport, endosome to Golgi. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34442 EVI5 Knockout cell line (HeLa) Human EVI5 1:3~1:6 Negative Online Inquiry
KO34443 EVI5 Knockout cell line (HCT 116) Human EVI5 1:2~1:4 Negative Online Inquiry
KO34444 EVI5 Knockout cell line (HEK293) Human EVI5 1:3~1:6 Negative Online Inquiry
KO34445 EVI5 Knockout cell line (A549) Human EVI5 1:3~1:4 Negative Online Inquiry

Background

EVI5 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the investigation of EVI5 gene function and its role in various biological processes. The EVI5 gene encodes a protein that is implicated in cellular proliferation, development, and oncogenic pathways. These knockout cell lines are generated using CRISPR-Cas9 technology, allowing for precise gene editing that results in the complete ablation of EVI5 expression. This targeted knockout enables researchers to study the phenotypic effects of EVI5 absence in a controlled environment, providing valuable insights into its physiological and pathological roles.

The primary function of EVI5 Gene Knockout Cell Lines is to serve as a functional platform for dissecting the molecular mechanisms underlying EVI5-related pathways. By observing the effects of gene deletion on cell behavior, signaling, and gene expression, researchers can elucidate EVI5’s contributions to tumor progression and other diseases. In clinical applications, understanding EVI5 can inform therapeutic targets and precision medicine approaches, particularly in oncology where aberrant signaling pathways play a crucial role.

What sets EVI5 Gene Knockout Cell Lines apart from conventional models is their unparalleled specificity and ease of use. Unlike traditional RNA interference methods, CRISPR-Cas9 provides a permanent modification of the genome without off-target effects, which enhances the reliability of research findings. Additionally, these cell lines are ready-to-use, minimizing preparation time and maximizing productivity for researchers seeking quick turnaround in their experimental timelines.

The value of EVI5 Gene Knockout Cell Lines extends beyond academic research; they have practical implications in drug discovery and biomarker identification. For clinicians and pharmaceutical companies, these models provide the critical data needed to develop targeted therapies and innovative treatment strategies.

Our company brings a wealth of expertise in cellular biology and gene editing technologies, ensuring that our products meet the highest quality standards. By offering EVI5 Gene Knockout Cell Lines, we empower researchers and healthcare professionals to advance their work with confidence, pushing the boundaries of scientific discovery and translational medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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