Gene: ETV4
Official Full Name: ETS variant transcription factor 4provided by HGNC
Gene Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of keratinocyte differentiation and positive regulation of transcription by RNA polymerase II. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09406 | ETV4 Knockout cell line (HeLa) | Human | ETV4 | 1:3~1:6 | Negative | Online Inquiry |
KO09407 | ETV4 Knockout cell line (HCT 116) | Human | ETV4 | 1:2~1:4 | Negative | Online Inquiry |
KO09408 | ETV4 Knockout cell line (A549) | Human | ETV4 | 1:3~1:4 | Negative | Online Inquiry |
ETV4 Gene Knockout Cell Lines are specialized biological tools designed to study the functional role of the ETV4 gene, which encodes a transcription factor involved in various cellular processes such as differentiation, proliferation, and cell migration. By employing cutting-edge gene-editing technologies like CRISPR/Cas9, these cell lines have been meticulously engineered to eliminate the expression of ETV4, allowing researchers to uncover its specific contributions to cellular dynamics and disease pathology.
The key function of ETV4 Gene Knockout Cell Lines lies in their ability to serve as a model system for investigating the molecular underpinnings of various conditions, including cancer metastasis and developmental disorders. By providing a clear comparison between ETV4-deficient and normal cells, scientists can elucidate the signaling pathways and biological mechanisms facilitated by ETV4. This comparative analysis is invaluable for translating basic research into clinical applications, such as the development of targeted therapies.
In terms of scientific importance, these knockout cell lines are instrumental in cancer research and regenerative medicine. They enable researchers to investigate the consequences of ETV4 loss on cellular behavior, identify potential therapeutic targets, and understand the roles of transcription factors in cell fate decisions.
The advantages of ETV4 Gene Knockout Cell Lines are significant when compared to traditional methods of gene silencing, such as RNA interference. Knockout models often provide a more stable and robust means of studying gene function, yielding clearer insights into the long-term effects of gene deletion on cellular physiology.
For researchers and clinicians, the value of these cell lines lies in their potential to accelerate the discovery of novel treatments and enhance our understanding of complex biological systems. By utilizing ETV4 knockout models, scientists can effectively bridge the gap between experimental research and clinical innovation.
As a leader in providing high-quality research reagents and services, our company is committed to advancing the life sciences field by delivering reliable, well-characterized products like the ETV4 Gene Knockout Cell Lines. Our expertise ensures that researchers have access to the tools they need to push the boundaries of scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.