Gene: ERMARD
Official Full Name: ER membrane associated RNA degradationprovided by HGNC
Gene Summary: The protein encoded by this gene contains 2 transmembrane domains near the C-terminus and is localized in the endoplasmic reticulum. Knockout of this gene in developing rat brain showed that it may be involved in neuronal migration. Mutations in this gene are associated with periventricular nodular heterotopia-6 (PVNH6). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17901 | ERMARD Knockout cell line (HeLa) | Human | ERMARD | 1:3~1:6 | Negative | Online Inquiry |
KO17902 | ERMARD Knockout cell line (HCT 116) | Human | ERMARD | 1:2~1:4 | Negative | Online Inquiry |
KO17903 | ERMARD Knockout cell line (HEK293) | Human | ERMARD | 1:3~1:6 | Negative | Online Inquiry |
KO17904 | ERMARD Knockout cell line (A549) | Human | ERMARD | 1:3~1:4 | Negative | Online Inquiry |
ERMARD Gene Knockout Cell Lines are advanced biological tools developed to create specific, targeted disruptions in the genetic material of cells. These cell lines are engineered to introduce precise knockouts of gene sequences, enabling researchers to study gene function and regulation in a controlled environment. This process uses state-of-the-art techniques such as CRISPR-Cas9 or RNA interference to ensure high efficiency and accuracy in gene editing.
The key function of ERMARD Gene Knockout Cell Lines is to allow scientists to investigate the phenotype and biological pathways associated with specific gene disruptions. By eliminating or mutating genes of interest, researchers can observe changes in cellular behavior, signaling pathways, and gene expression profiles. This biotechnological advancement is crucial for elucidating the roles of genes in development, disease progression, and drug response, which can significantly contribute to the fields of genomics, molecular biology, and therapeutic development.
The scientific importance of these knockout cell lines is underscored by their wide-ranging applications in both basic and applied research settings. In academia, they serve as essential models for genetic studies, while in clinical research, they facilitate the exploration of novel treatment strategies for genetic disorders and various forms of cancer. By providing a clear and reproducible system for gene disruption, ERMARD Gene Knockout Cell Lines are instrumental in advancing our knowledge of gene function and its implications in health and disease.
One of the standout advantages of ERMARD Gene Knockout Cell Lines is their rigorously validated knockout efficiency and specificity. Compared to conventional knockout models, like transgenic mice, these cell lines offer a more rapid and cost-effective approach, requiring significantly less time and resources. Additionally, they can be easily manipulated for large-scale experiments and applied across various cell types, making them more versatile than many existing alternatives.
Researchers and clinicians alike will find that the ERMARD Gene Knockout Cell Lines provide essential insights into cell biology and genetics, enabling the identification of potential therapeutic targets and the development of innovative treatments. As a leading provider in biological research tools, our company is dedicated to offering high-quality products backed by extensive scientific expertise, ensuring that our customers are equipped to push the boundaries of scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.