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ENTREP3 Knockout Cell Lines

Gene: ENTREP3

Official Full Name: endosomal transmembrane epsin interactor 3provided by HGNC

Gene Summary: This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17966 ENTREP3 Knockout cell line (HeLa) Human ENTREP3 1:3~1:6 Negative Online Inquiry
KO17967 ENTREP3 Knockout cell line (HCT 116) Human ENTREP3 1:2~1:4 Negative Online Inquiry
KO17968 ENTREP3 Knockout cell line (HEK293) Human ENTREP3 1:3~1:6 Negative Online Inquiry
KO17969 ENTREP3 Knockout cell line (A549) Human ENTREP3 1:3~1:4 Negative Online Inquiry

Background

ENTREP3 Gene Knockout Cell Lines are innovative biological tools designed to enable precise genomic modifications for in-depth research into gene function and associated pathways. Developed using advanced CRISPR-Cas9 technology, these cell lines have undergone targeted disruption of the ENTREP3 gene, which plays a pivotal role in various biological processes, including cellular metabolism and signaling pathways. By providing researchers with a reliable model for understanding gene function, ENTREP3 Knockout Cell Lines facilitate the investigation of gene-related diseases, drug responses, and potential therapeutic interventions.

The primary mechanism by which ENTREP3 Knockout Cell Lines operate is through the introduction of specific mutations that inactivate the gene of interest. This inactivation allows for the observation of phenotypic changes and molecular alterations in cellular behavior, thereby shedding light on the gene's role within the broader biological context. As such, these cell lines serve as invaluable assets for studies in genetics, molecular biology, and pharmacology.

In the realm of scientific research and clinical applications, ENTREP3 Knockout Cell Lines possess substantial importance. They can aid in elucidating disease mechanisms, enabling the development of novel therapeutics, and offering insights into personalized medicine approaches. By utilizing these cell lines, researchers can identify biomarkers and potential drug targets, significantly enhancing the capacity for innovative treatment strategies.

What sets ENTREP3 Gene Knockout Cell Lines apart from traditional models is their high specificity and efficiency, coupled with the robustness of the CRISPR technology. Unlike earlier gene knockdown methods, which may offer incomplete or transient effects, these knockout lines provide stable and permanent alterations, leading to more reliable experimental outcomes. This feature increases the reproducibility and credibility of research findings, making them compelling tools for advancing scientific knowledge.

For researchers and clinicians striving for groundbreaking discoveries and meaningful applications, the value of ENTREP3 Gene Knockout Cell Lines cannot be overstated. The ability to dissect complex biological questions through a well-characterized, high-fidelity model provides a unique edge in today's rapidly evolving research landscape. Our company specializes in the development and distribution of cutting-edge biological products, ensuring that we deliver high-quality tools that empower researchers in their quest for scientific advancements. With a commitment to excellence, we drive innovation to support your research objectives.

Please note that all services are for research use only. Not intended for any clinical use.

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