Gene: ENTPD6
Official Full Name: ectonucleoside triphosphate diphosphohydrolase 6provided by HGNC
Gene Summary: ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which are characteristic of NTPases. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38637 | ENTPD6 Knockout cell line (HeLa) | Human | ENTPD6 | 1:3~1:6 | Negative | Online Inquiry |
KO38638 | ENTPD6 Knockout cell line (HCT 116) | Human | ENTPD6 | 1:2~1:4 | Negative | Online Inquiry |
KO38639 | ENTPD6 Knockout cell line (HEK293) | Human | ENTPD6 | 1:3~1:6 | Negative | Online Inquiry |
KO38640 | ENTPD6 Knockout cell line (A549) | Human | ENTPD6 | 1:3~1:4 | Negative | Online Inquiry |
ENTPD6 Gene Knockout Cell Lines represent an innovative research tool designed for the comprehensive study of cellular mechanisms modulated by the ENTPD6 gene, which encodes ecto-nucleotide triphosphate diphosphohydrolase 6. This enzyme plays a crucial role in nucleotide metabolism and regulation of purinergic signaling pathways. By creating these knockout cell lines, researchers can examine the gene's impact on cell proliferation, differentiation, and apoptosis, allowing for greater insights into physiological and pathological processes.
The key functionality of these knockout cell lines lies in their ability to facilitate elucidation of the ENTPD6 gene's regulatory mechanisms. The genetic alteration leads to the absence of the ENTPD6 enzyme, resulting in altered extracellular ATP levels and subsequent effects on purinergic receptor activation. This unique mechanism provides a valuable platform for investigating therapeutic strategies aimed at manipulating purinergic signaling in various diseases, including cancer, inflammation, and neurodegenerative disorders.
In terms of scientific importance, the ENTPD6 Gene Knockout Cell Lines have significant applications in both research and clinical settings. They enable scientists to explore novel treatment modalities that could target pathways involving ATP metabolism and its receptor-mediated effects, contributing to the development of advanced pharmacotherapies. Furthermore, these cell lines serve as a vital resource for biomedicine, promoting the translation of basic research findings into clinical therapies.
What sets ENTPD6 Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. Unlike transient knockdown approaches, these stable knockout lines ensure consistent and reproducible results, making them indispensable for longitudinal studies. Additionally, they can potentially reduce experimental variability, allowing researchers to draw clearer conclusions about the gene's function and its therapeutic potential.
The value of ENTPD6 Gene Knockout Cell Lines to researchers and clinicians is underscored by the growing interest in purinergic signaling pathways, highlighting their relevance in contemporary biomedical research. Utilizing these cell lines enhances the ability to dissect complex biological networks, leading to discoveries that could inform new treatment strategies for various diseases.
Our expertise in generating high-quality biological products ensures that your research is backed by reliable tools. With a commitment to advancing scientific knowledge, we offer robust and meticulously validated ENTPD6 Gene Knockout Cell Lines, empowering researchers to push the boundaries of what is possible in the field of cell biology and therapeutic discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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