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EMSY Knockout Cell Lines

Gene: EMSY

Official Full Name: EMSY transcriptional repressor, BRCA2 interactingprovided by HGNC

Gene Summary: Predicted to enable identical protein binding activity. Predicted to be involved in DNA repair; chromatin organization; and regulation of DNA-templated transcription. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18004 EMSY Knockout cell line (HeLa) Human EMSY 1:3~1:6 Negative Online Inquiry
KO18005 EMSY Knockout cell line (HCT 116) Human EMSY 1:2~1:4 Negative Online Inquiry
KO18006 EMSY Knockout cell line (HEK293) Human EMSY 1:3~1:6 Negative Online Inquiry
KO18007 EMSY Knockout cell line (A549) Human EMSY 1:3~1:4 Negative Online Inquiry

Background

EMSY Gene Knockout Cell Lines are precision-engineered cellular models designed to facilitate the investigation of gene function and regulation by offering a complete ablation of the EMSY gene. These cell lines employ the state-of-the-art CRISPR-Cas9 technology, ensuring that the target gene is accurately and efficiently disrupted, resulting in a consistent phenotype across different experiments. The knockout of the EMSY gene is crucial for studying its role in oncogenesis and its interactions within various signaling pathways, particularly in cancer biology research.

The mechanism by which EMSY Gene Knockout Cell Lines operate involves a targeted double-strand break in the DNA sequence of the EMSY gene, followed by the cell's error-prone repair process, leading to insertions or deletions that disrupt the gene's coding sequence. This results in a loss of function, enabling scientists to analyze the downstream effects of gene knockout on cellular behavior, proliferation, and response to drugs. Such cellular models are not only pivotal for functional genomics but also serve as essential tools in drug discovery and development.

The scientific importance of EMSY Gene Knockout Cell Lines extends into various applications, including cancer research, gene therapy, and the study of genetic disorders. By utilizing these cell lines, researchers can elucidate the molecular mechanisms underlying tumorigenesis and assess the efficacy of potential therapeutic compounds targeting the EMSY pathway.

What sets EMSY Gene Knockout Cell Lines apart from alternative models is their high reproducibility and specificity. Unlike traditional methods of gene disruption, such as RNA interference, which can lead to off-target effects and incomplete suppression, our knockout cell lines provide a robust framework for gene analysis with minimal variability. Researchers can rely on these models for achieving definitive results, thereby enhancing the integrity of their findings.

For both researchers and clinicians, the value of EMSY Gene Knockout Cell Lines lies in their ability to streamline experiments and generate reliable data that is crucial for advancing our understanding of complex biological systems. Moreover, the potential for these cell lines to contribute to translational research projects underscores their broader importance in the clinical setting.

Backed by our company's extensive experience in genetic engineering and commitment to innovation, EMSY Gene Knockout Cell Lines represent a powerful asset for advancing your research initiatives and unlocking new frontiers in biomedicine.

Please note that all services are for research use only. Not intended for any clinical use.

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