Gene: EMC9
Official Full Name: ER membrane protein complex subunit 9provided by HGNC
Gene Summary: Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Located in cytoplasm. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00038 | EMC9 Knockout cell line (293T) | Human | EMC9 | 1:3~1:6 | Negative | Online Inquiry |
KO00425 | EMC9 knockout cell line (HEK293) | Human | EMC9 | 1:3~1:6 | Negative | Online Inquiry |
KO23161 | EMC9 Knockout cell line (HeLa) | Human | EMC9 | 1:3~1:6 | Negative | Online Inquiry |
KO23162 | EMC9 Knockout cell line (HCT 116) | Human | EMC9 | 1:2~1:4 | Negative | Online Inquiry |
KO23163 | EMC9 Knockout cell line (A549) | Human | EMC9 | 1:3~1:4 | Negative | Online Inquiry |
EMC9 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the EMC9 gene's role in cellular processes. By employing CRISPR-Cas9 gene-editing technology, these cell lines have been precisely modified to disrupt the EMC9 gene, allowing researchers to observe the consequences of its absence in a controlled environment. This knockout model provides invaluable insight into the gene's functions, particularly in relation to protein sorting and intracellular transport mechanisms, offering a clearer understanding of its impact on cellular homeostasis.
The EMC9 protein is known to be involved in the regulation of various cellular pathways, and the knockout cell lines enable researchers to investigate alterations in these pathways. Key mechanisms include the disruption of endosomal-lysosomal trafficking, leading to potential implications in neurodegenerative diseases and cancer biology. This model is not only essential for elucidating the biological roles of EMC9 but also serves as a platform for high-throughput drug screening, providing a systematic approach to evaluating therapeutic candidates targeting related pathways.
In the context of research and clinical settings, EMC9 Gene Knockout Cell Lines offer significant advantages over traditional cell models. They allow for precise manipulation of the gene of interest, leading to more reproducible and relevant data when studying gene function and drug responses. These cell lines stand out for their ease of use and genetic stability, minimizing the time and resources typically required for gene editing.
For researchers and clinicians focused on understanding gene function and its implications in health and disease, the EMC9 Gene Knockout Cell Lines represent a cutting-edge tool that enhances experimental design and outcomes. Our company is dedicated to advancing biotechnological innovation, backed by a robust background in genetic engineering and cell line development, thereby ensuring you have access to the highest quality products tailored to your research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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