Gene: EHMT2
Official Full Name: euchromatic histone lysine methyltransferase 2provided by HGNC
Gene Summary: This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03436 | EHMT2 Knockout cell line (HeLa) | Human | EHMT2 | 1:3~1:6 | Negative | Online Inquiry |
KO03437 | EHMT2 Knockout cell line (HCT 116) | Human | EHMT2 | 1:2~1:4 | Negative | Online Inquiry |
KO03438 | EHMT2 Knockout cell line (HEK293) | Human | EHMT2 | 1:3~1:6 | Negative | Online Inquiry |
KO03439 | EHMT2 Knockout cell line (A549) | Human | EHMT2 | 1:3~1:4 | Negative | Online Inquiry |
EHMT2 Gene Knockout Cell Lines represent a groundbreaking advancement in the study of gene function and regulation, specifically targeting the EHMT2 gene, which is implicated in various physiological processes including chromatin remodeling and gene expression regulation. These cell lines are engineered to contain specific deletions in the EHMT2 gene, providing a vital tool for researchers interested in elucidating the biological consequences of EHMT2 loss.
The key function of EHMT2 is its role as a histone methyltransferase, which is critical in modifying chromatin structure and thereby influencing gene transcription. By utilizing these knockout cell lines, scientists can investigate the resultant phenotypic changes and elucidate the pathways affected by EHMT2 disruption. This mechanistic understanding is invaluable in both fundamental research and translational studies, particularly in the context of diseases like cancer, where chromatin remodeling plays a significant role in tumorigenesis.
In terms of scientific importance, EHMT2 Gene Knockout Cell Lines serve as an essential model for exploring gene function and its implications in various biological processes. Their use in research may lead to potential therapeutic targets for conditions associated with aberrant regulation of gene expression. Moreover, these cell lines are compatible with a range of experimental applications, including drug discovery, genetic interaction studies, and functional genomics.
Compared to alternative models such as wild-type cell lines or other gene knockout systems, the EHMT2 Gene Knockout Cell Lines offer researchers a more specific tool for studying the exact effects of EHMT2 knockdown, providing a clearer understanding of its role in cellular processes. Furthermore, the robust validation of these cell lines ensures reproducibility and reliability in experimental design.
For researchers and clinicians, the value of EHMT2 Gene Knockout Cell Lines lies in their ability to facilitate cutting-edge research, ultimately contributing to advancements in cellular biology and therapeutic development. The ease of use and adaptability of these lines means they can seamlessly integrate into existing research workflows.
Our company prides itself on its expertise in providing high-quality biological products and tools, ensuring that researchers have access to reliable resources necessary for their groundbreaking work. With a commitment to exceptional service and innovative solutions, we are dedicated to advancing scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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