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EHD3 Knockout Cell Lines

Gene: EHD3

Official Full Name: EH domain containing 3provided by HGNC

Gene Summary: Predicted to enable nucleic acid binding activity. Involved in several processes, including cytosolic transport; endocytic recycling; and protein homooligomerization. Acts upstream of or within protein localization to plasma membrane and regulation of cardiac muscle cell membrane potential. Located in ciliary pocket membrane and recycling endosome membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26722 EHD3 Knockout cell line (HEK293) Human EHD3 1:3~1:6 Negative Online Inquiry
KO26723 EHD3 Knockout cell line (A549) Human EHD3 1:3~1:4 Negative Online Inquiry

Background

EHD3 Gene Knockout Cell Lines represent a pioneering biological tool designed for investigating the role of the EHD3 gene in cellular processes. EHD3, or EH domain-containing protein 3, is implicated in various cellular functions, including endocytosis, membrane trafficking, and signal transduction. Our gene knockout cell lines utilize CRISPR-Cas9 technology to achieve precise deletion of the EHD3 gene, allowing researchers to assess the gene’s impact on cellular physiology and identify potential therapeutic targets.

The principal function of these knockout cell lines is to provide a controlled environment for studying the biological consequences of EHD3 depletion. When the gene is knocked out, researchers can observe changes in cellular morphology and function, as well as alterations in biochemical pathways associated with membrane dynamics. This enables the elucidation of the gene’s role in diverse biological mechanisms such as apoptosis, proliferation, and migration, making it a critical tool for advanced research in cell biology.

The scientific significance of EHD3 Gene Knockout Cell Lines extends beyond basic research; they are invaluable in clinical settings, particularly in the development and validation of targeted therapies for diseases related to cellular dysfunction, including cancer and neurodegenerative disorders. By isolating the effects of the EHD3 gene, researchers can refine drug discovery processes, allowing for the development of more effective intervention strategies.

Compared to conventional methods, such as RNA interference or transgenic approaches, our EHD3 Gene Knockout Cell Lines offer unparalleled specificity and efficiency in gene editing. The robust performance of these cell lines, coupled with their ease of use, ensures that researchers can achieve reliable, reproducible results in their experiments.

For researchers and clinicians committed to advancing their understanding of cellular mechanisms and drug discovery, EHD3 Gene Knockout Cell Lines provide a powerful tool that stands out in both academic and clinical settings. Our company prides itself on its commitment to quality and innovation in the biotechnological landscape, making these gene knockout cell lines a cornerstone for those seeking to uncover the intricacies of cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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