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EHBP1 Knockout Cell Lines

Gene: EHBP1

Official Full Name: EH domain binding protein 1provided by HGNC

Gene Summary: This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09572 EHBP1 Knockout cell line (HeLa) Human EHBP1 1:3~1:6 Negative Online Inquiry
KO09573 EHBP1 Knockout cell line (HCT 116) Human EHBP1 1:2~1:4 Negative Online Inquiry
KO09574 EHBP1 Knockout cell line (HEK293) Human EHBP1 1:3~1:6 Negative Online Inquiry
KO09575 EHBP1 Knockout cell line (A549) Human EHBP1 1:3~1:4 Negative Online Inquiry

Background

EHBP1 Gene Knockout Cell Lines are advanced, genetically engineered tools designed to facilitate the study of the EHBP1 (Eps15 Homology Domain-Binding Protein 1) gene's role in cellular processes. EHBP1 is implicated in endocytosis and actin organization, making its knockout variants essential for discerning its functional contributions to various cellular mechanisms. These knockout cell lines are generated through CRISPR-Cas9 technology, which enables precise gene editing, allowing researchers to create cell lines devoid of EHBP1 expression, thereby isolating its effects on cellular dynamics.

The primary function of the EHBP1 Gene Knockout Cell Lines is to serve as a model for understanding how the absence of EHBP1 affects cellular processes such as membrane trafficking, cytoskeletal rearrangement, and signal transduction pathways. By studying these cell lines, researchers can elucidate the molecular pathways that EHBP1 governs, thereby gaining insights into its potential roles in pathologies like cancer and neurodegenerative diseases.

The scientific importance of these cell lines is underscored by their versatility in both academic and clinical research settings. As cellular models, they are foundational for drug discovery, mechanism of action studies, and pathophysiological investigations. Unlike traditional methods, the precise knockout of EHBP1 facilitates clear delineation of its functions without the confounding effects of residual gene expression.

In comparison to alternatives such as RNA interference, which can yield incomplete knockdown effects, the EHBP1 Gene Knockout Cell Lines offer a complete elimination of the target gene. This enhances the reliability of experimental results, making them a superior choice for rigorous scientific inquiry.

Researchers and clinicians will find these cell lines invaluable as they provide a robust platform for uncovering critical insights and potential therapeutic targets related to EHBP1. Our company prides itself on providing high-quality biological products, backed by a commitment to innovation and scientific excellence, ensuring that users have access to the best tools for their research and development initiatives.

Please note that all services are for research use only. Not intended for any clinical use.

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