Home / EFNB2 Knockout Cell Lines

EFNB2 Knockout Cell Lines

Gene: EFNB2

Official Full Name: ephrin B2provided by HGNC

Gene Summary: This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38099 EFNB2 Knockout cell line (HeLa) Human EFNB2 1:3~1:6 Negative Online Inquiry
KO38100 EFNB2 Knockout cell line (HCT 116) Human EFNB2 1:2~1:4 Negative Online Inquiry
KO38101 EFNB2 Knockout cell line (HEK293) Human EFNB2 1:3~1:6 Negative Online Inquiry
KO38102 EFNB2 Knockout cell line (A549) Human EFNB2 1:3~1:4 Negative Online Inquiry

Background

EFNB2 Gene Knockout Cell Lines are advanced research tools designed to facilitate the functional analysis of EFNB2, a critical gene implicated in various biological processes, including cell differentiation and signal transduction pathways. By creating knockout models, researchers can effectively eliminate the expression of the EFNB2 gene, allowing for in-depth studies of its role in cellular biology and disease mechanisms.

These cell lines utilize CRISPR-Cas9 gene editing technology to achieve highly efficient and specific gene disruption. The knockout of EFNB2 enables scientists to explore its involvement in fundamental processes such as angiogenesis, neuronal development, and immune response regulation. The precise genome editing provided by these cell lines leads to a more accurate representation of gene function, facilitating investigations that may contribute to understanding various pathologies, including cancers and neurological disorders.

The scientific significance of EFNB2 Gene Knockout Cell Lines extends to their broad applicability in both research laboratories and clinical settings. Researchers can utilize these models to validate potential drug targets, assess the molecular mechanisms underpinning pathologies, and develop therapeutics aimed at modulating EFNB2-related pathways. Additionally, the consistent performance of these cell lines underpins their utility in high-throughput screening applications.

Distinct from alternative models, such as transient transfection systems or traditional knockout models that may exhibit off-target effects or variable expression, EFNB2 Gene Knockout Cell Lines provide stable, reproducible results suitable for longitudinal studies. This increases the reliability of experimental outputs and subsequently enhances the pathway to translating findings into therapeutic advancements.

For researchers and clinicians focused on unraveling the complexities of EFNB2-related functions, employing these knockout cell lines represents a strategic advantage. Our company specializes in creating high-quality biological products tailored for cutting-edge research, backed by robust expertise in gene editing technologies. With a commitment to advancing scientific discovery, we strive to equip the research community with tools that drive innovative solutions in biomedical research and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.