Gene: EEF1AKMT1
Official Full Name: EEF1A lysine methyltransferase 1provided by HGNC
Gene Summary: Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27541 | EEF1AKMT1 Knockout cell line (HeLa) | Human | EEF1AKMT1 | 1:3~1:6 | Negative | Online Inquiry |
KO27542 | EEF1AKMT1 Knockout cell line (HCT 116) | Human | EEF1AKMT1 | 1:2~1:4 | Negative | Online Inquiry |
KO27543 | EEF1AKMT1 Knockout cell line (HEK293) | Human | EEF1AKMT1 | 1:3~1:6 | Negative | Online Inquiry |
KO27544 | EEF1AKMT1 Knockout cell line (A549) | Human | EEF1AKMT1 | 1:3~1:4 | Negative | Online Inquiry |
EEF1AKMT1 Gene Knockout Cell Lines are specialized cellular models engineered to silence the expression of the EEF1AKMT1 gene through targeted gene knockout techniques. This gene encodes for a specific methyltransferase involved in post-translational modifications that impact protein synthesis and stability. The knockout of this gene allows researchers to investigate its role in various biological processes, including cellular stress response, protein synthesis regulation, and translational fidelity.
Upon creation, the EEF1AKMT1 knockout cell lines exhibit altered mechanisms leading to the accumulation of specific proteins and modifications in translational activities. The absence of EEF1AKMT1 not only elucidates its function in eukaryotic protein synthesis but also serves as a model for studying diseases associated with aberrant protein methylation. These cell lines can significantly contribute to research in cancer biology, neurodegenerative diseases, and metabolic disorders.
In clinical and research settings, the use of these knockout cell lines provides invaluable insights into the molecular pathways that govern cellular responses to various stimuli. Moreover, they facilitate drug discovery by serving as models for screening potential therapeutics targeting related pathways.
Compared to other gene knockout systems, EEF1AKMT1 Gene Knockout Cell Lines provide a unique advantage by offering a precisely controlled model that expresses relevant phenotypes, reducing the variability often found in traditional systems. This specificity empowers researchers to gather clearer data on biological interactions and therapeutic strategies.
For researchers and clinicians, the availability of EEF1AKMT1 Gene Knockout Cell Lines represents a significant tool in their arsenal against diseases driven by protein synthesis dysregulation. The ability to manipulate and study the effects of specific gene silencing enhances experimental reproducibility and drives forward the understanding of complex biological systems.
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