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EDA2R Knockout Cell Lines

Gene: EDA2R

Official Full Name: ectodysplasin A2 receptorprovided by HGNC

Gene Summary: The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18074 EDA2R Knockout cell line (HEK293) Human EDA2R 1:3~1:6 Negative Online Inquiry
KO18075 EDA2R Knockout cell line (A549) Human EDA2R 1:3~1:4 Negative Online Inquiry

Background

EDA2R Gene Knockout Cell Lines represent a groundbreaking tool in genetic research, specifically engineered to facilitate the study of the ectodysplasin A2 receptor (EDA2R) gene and its associated pathways. These cell lines have been developed through precise genetic engineering techniques to selectively disrupt the EDA2R gene, allowing researchers to investigate the functional consequences of its absence in a controlled environment.

The key mechanisms at play involve the targeted CRISPR/Cas9 gene-editing technology, which introduces specific mutations to eliminate the expression of EDA2R protein. This precise knockout enables scientists to explore the role of EDA2R in various biological processes, such as cellular signaling, development, and tissue morphology. By utilizing these cell lines, researchers can conduct essential experiments to elucidate the gene's implications in disorders related to ectodermal dysplasia and other conditions linked to developmental anomalies.

Scientifically, EDA2R Gene Knockout Cell Lines have valuable applications in both research and clinical settings. They serve as vital models for drug screening, biomarker identification, and therapeutic intervention strategies aimed at mitigating the effects of EDA2R-associated pathologies. What distinguishes our product is its unparalleled specificity and reproducibility, ensuring that researchers obtain reliable and consistent results that are crucial for advancing scientific knowledge and therapeutic development.

Furthermore, our EDA2R Gene Knockout Cell Lines come with extensive technical support, robust characterization data, and optimized culture conditions that facilitate seamless integration into any laboratory workflow. This makes them an invaluable addition to any research portfolio focused on genetic and cellular biology. With a longstanding commitment to innovation and quality in the field of biological products, our company is dedicated to equipping researchers and clinicians with cutting-edge tools that drive scientific discovery and improve health outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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