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EAPP Knockout Cell Lines

Gene: EAPP

Official Full Name: E2F associated phosphoproteinprovided by HGNC

Gene Summary: This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18089 EAPP Knockout cell line (HeLa) Human EAPP 1:3~1:6 Negative Online Inquiry
KO18090 EAPP Knockout cell line (HCT 116) Human EAPP 1:2~1:4 Negative Online Inquiry
KO18091 EAPP Knockout cell line (HEK293) Human EAPP 1:3~1:6 Negative Online Inquiry
KO18092 EAPP Knockout cell line (A549) Human EAPP 1:3~1:4 Negative Online Inquiry

Background

EAPP Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically engineered to facilitate the study of gene function and associated cellular pathways. These cell lines are derived from specific mammalian models where the EAPP gene has been strategically inactivated through advanced genome-editing techniques, such as CRISPR/Cas9. By offering a platform to investigate the biological roles of EAPP, these cell lines allow researchers to delve into the gene's contributions to various physiological processes, including cellular stress responses and signal transduction.

The primary function of the EAPP Gene Knockout Cell Lines lies in their ability to mimic in vivo gene inactivation, providing insights into essential cellular mechanisms. Researchers can utilize these models to understand alterations in gene expression, investigate downstream signaling pathways, and evaluate the effects of potential therapeutic compounds—yielding important data that can influence drug development and disease treatment strategies.

In scientific and clinical arenas, the applications of EAPP Gene Knockout Cell Lines are vast. These models can be instrumental in elucidating the pathophysiology of diseases such as cancer, neurodegenerative disorders, and metabolic syndromes, understanding how loss of EAPP function contributes to disease progression. Such insights are critical for the development of targeted therapies and personalized medicine approaches, positioning these cell lines at the forefront of translational research.

What sets EAPP Gene Knockout Cell Lines apart from traditional cell models is their precise genetic modification and the robustness of data they yield, thus minimizing experimental variability and enhancing reproducibility in research. These lines are also validated for consistent performance, ensuring that scientists can trust the integrity of their findings.

For researchers and clinicians aiming to unlock the intricacies of gene function or pave the way for innovative therapies, these knockout cell lines are invaluable. Their high fidelity in simulating gene disruptions offers a reliable pathway to groundbreaking discoveries, making them a vital addition to any laboratory specializing in genetic research.

Our company prides itself on its expertise in producing high-quality, genetically engineered cell lines. With a commitment to advancing scientific knowledge, we provide tools that help researchers push the boundaries of discovery and improve healthcare outcomes through innovative solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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