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DYNLT2 Knockout Cell Lines

Gene: DYNLT2

Official Full Name: dynein light chain Tctex-type 2provided by HGNC

Gene Summary: Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be located in cytosol and sperm flagellum. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18114 DYNLT2 Knockout cell line (HeLa) Human DYNLT2 1:3~1:6 Negative Online Inquiry
KO18115 DYNLT2 Knockout cell line (HCT 116) Human DYNLT2 1:2~1:4 Negative Online Inquiry
KO18116 DYNLT2 Knockout cell line (A549) Human DYNLT2 1:3~1:4 Negative Online Inquiry

Background

DYNLT2 Gene Knockout Cell Lines are a specialized set of cellular models generated through targeted gene editing techniques, specifically designed to study the functional roles of the DYNLT2 gene in various biological processes. These knockout cell lines provide an invaluable tool for dissecting the physiological and pathological roles of DYNLT2, a member of the dynein light chain family that is crucial for intracellular transport and cellular signaling.

The key function of DYNLT2 is its involvement in retrograde transport, where it plays an essential role in the movement of organelles and vesicles along the microtubule cytoskeleton. By knocking out the DYNLT2 gene, researchers can gain insights into cellular dynamics, the regulatory mechanisms of intracellular transport, and how perturbations in these pathways can lead to disease states, particularly neurodegenerative disorders. Understanding these mechanisms can elucidate the role of DYNLT2 in cellular stress responses and signal transduction.

From a scientific perspective, DYNLT2 Gene Knockout Cell Lines are pivotal for both basic and applied research. They enable scientists to model pathological conditions associated with DYNLT2 dysfunction, thereby informing drug discovery and therapeutic interventions. The knockout models facilitate comprehensive studies involving gene expression profiling, protein interaction assessments, and mechanistic investigations that would otherwise be impossible in unmodified cell lines.

Compared to other knockout models, our DYNLT2 Gene Knockout Cell Lines stand out due to the high efficiency of gene editing and the reproducibility of experimental outcomes. These cell lines are meticulously validated, ensuring that the absence of the DYNLT2 gene is not only confirmed but also results in predictable phenotypic changes. This reliability provides researchers with the confidence necessary to explore novel hypotheses surrounding DYNLT2 function.

Investing in DYNLT2 Gene Knockout Cell Lines presents a significant opportunity for researchers and clinicians aiming to unravel complex biological pathways and develop targeted therapies. The ability to manipulate gene expression precisely empowers researchers to create a deeper understanding of disease mechanisms, furthering the potential for innovations in treatment strategies.

Our company has extensive expertise in developing cutting-edge biological products tailored to meet the demands of contemporary research needs. Our commitment to quality and innovation ensures that our products, including the DYNLT2 Gene Knockout Cell Lines, significantly contribute to advancing scientific understanding and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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