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DYNLL2 Knockout Cell Lines

Gene: DYNLL2

Official Full Name: dynein light chain LC8-type 2provided by HGNC

Gene Summary: Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based process. Located in 9+0 non-motile cilium and centrosome. Is active in glutamatergic synapse and postsynapse. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02053 DYNLL2 Knockout cell line (HeLa) Human DYNLL2 1:3~1:6 Negative Online Inquiry
KO02054 DYNLL2 Knockout cell line (HCT 116) Human DYNLL2 1:2~1:4 Negative Online Inquiry
KO02055 DYNLL2 Knockout cell line (HEK293) Human DYNLL2 1:3~1:6 Negative Online Inquiry
KO02056 DYNLL2 Knockout cell line (A549) Human DYNLL2 1:3~1:4 Negative Online Inquiry

Background

DYNLL2 Gene Knockout Cell Lines are specially engineered cellular systems in which the DYNLL2 gene has been disrupted to study its specific biological functions. DYNLL2 encodes a member of the dynein light chain family, which plays a pivotal role in intracellular transport processes, particularly in mediating the attachment of various motor proteins to cellular components. The knockout of this gene allows researchers to investigate the loss-of-function phenotypes and to understand the underlying cellular pathways influenced by DYNLL2, including cellular differentiation, motility, and response to stress.

The primary mechanism by which these cell lines function involves the ablation of DYNLL2 activity, leading to observable changes in cytoskeletal dynamics and phagocytosis. Researchers can analyze the effects on cargo transport mechanisms, cell signaling pathways, and other functions essential for cell behavior and homeostasis. This product is crucial for advancing our understanding of various physiological and pathological conditions related to cytoskeletal dysfunction and motor protein activity.

DYNLL2 Gene Knockout Cell Lines offer significant advantages over traditional cell models, as they provide a targeted approach to studying the gene's effects with high specificity and reproducibility. Unlike general knockdown methods, knockout lines facilitate a deeper understanding of gene function and its role in disease mechanisms. Additionally, these cell lines are valuable tools for drug discovery and therapeutic development, allowing for high-throughput screening of potential pharmacological agents that may modulate DYNLL2-associated pathways.

The uniqueness of DYNLL2 Gene Knockout Cell Lines lies in their ability to offer a controllable and stable platform for experimental manipulation, making them indispensable in research environments focused on molecular biology, cell biology, and translational medicine. With this product, researchers and clinicians can enhance their investigations into gene function, cellular physiology, and resultant therapeutic interventions.

Our company specializes in providing state-of-the-art biological products that facilitate groundbreaking research. We are committed to empowering the scientific community with high-quality tools, such as the DYNLL2 Gene Knockout Cell Lines, to accelerate discoveries and improve clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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