Gene: DYNC1LI2
Official Full Name: dynein cytoplasmic 1 light intermediate chain 2provided by HGNC
Gene Summary: Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995 [PubMed 7738094]). See DYNC1H1 (MIM 600112) for general information about dyneins.[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38200 | DYNC1LI2 Knockout cell line (HeLa) | Human | DYNC1LI2 | 1:3~1:6 | Negative | Online Inquiry |
KO38201 | DYNC1LI2 Knockout cell line (HCT 116) | Human | DYNC1LI2 | 1:2~1:4 | Negative | Online Inquiry |
KO38202 | DYNC1LI2 Knockout cell line (HEK293) | Human | DYNC1LI2 | 1:3~1:6 | Negative | Online Inquiry |
KO38203 | DYNC1LI2 Knockout cell line (A549) | Human | DYNC1LI2 | 1:3~1:4 | Negative | Online Inquiry |
DYNC1LI2 Gene Knockout Cell Lines are sophisticated, genetically engineered models specifically designed to elucidate the role of the DYNC1LI2 gene in cellular processes. By employing CRISPR-Cas9 technology, these cell lines have achieved a complete knockout of the DYNC1LI2 gene, enabling researchers to investigate the functional consequences of its absence. DYNC1LI2, a critical gene encoding a cytoplasmic dynein light intermediate chain, is integral to intracellular transport and spindle organization during cell division.
The primary function of these knockout cell lines lies in their ability to allow researchers to explore the mechanistic pathways linked to DYNC1LI2 without the confounding influences of its expression. This offers a unique platform to study cellular dynamics, neurodegenerative diseases, and various cancer models, thereby advancing our understanding of these complex biological systems. The precise absence of DYNC1LI2 allows for the differentiation of pathways that may be dependent or independent of the gene's functioning, facilitating more targeted research.
From a scientific viewpoint, the DYNC1LI2 Gene Knockout Cell Lines have significant implications in both basic and applied research. Their applications range from examining cellular transport mechanisms to investigating the pathophysiological roles in neurodegeneration, thereby attracting the interest of both academic researchers and pharmaceutical developers seeking to design innovative therapeutic strategies.
One of the standout advantages of our DYNC1LI2 Gene Knockout Cell Lines is their high fidelity and reproducibility, coupled with ready availability for experimentation. This contrasts sharply with traditional methods of gene knockout, which often involve prolonged and complex breeding of transgenic models. Researchers can rapidly generate experimental data without the need for extensive preliminary work, maximizing efficiency and accelerating discovery timelines.
Valuable to clinicians and researchers alike, these cell lines pave the way for significant advancements in understanding diseases that involve dysregulated cellular transport and division. By choosing our DYNC1LI2 Gene Knockout Cell Lines, users are not only investing in a research tool but also contributing to a broader scientific endeavor aimed at unlocking therapeutic avenues.
Our company specializes in providing cutting-edge biological research tools backed by extensive expertise in genetic engineering and cell line development. We are committed to supporting your research objectives with reliable products designed to propel innovative discoveries in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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