Gene: DUSP13A
Official Full Name: dual specificity phosphatase 13Aprovided by HGNC
Gene Summary: Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This gene encodes a dual specificity phosphatase that acts on both phosphotyrosine and phosphoserine/threonine residues. The encoded protein is expressed in skeletal muscle. [provided by RefSeq, Mar 2023]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18137 | DUSP13A Knockout cell line (HeLa) | Human | DUSP13A | 1:3~1:6 | Negative | Online Inquiry |
KO18138 | DUSP13A Knockout cell line (HCT 116) | Human | DUSP13A | 1:2~1:4 | Negative | Online Inquiry |
KO18139 | DUSP13A Knockout cell line (HEK293) | Human | DUSP13A | 1:3~1:6 | Negative | Online Inquiry |
KO18140 | DUSP13A Knockout cell line (A549) | Human | DUSP13A | 1:3~1:4 | Negative | Online Inquiry |
DUSP13A Gene Knockout Cell Lines are engineered cellular models specifically created to study the functional implications of the DUSP13A gene, which encodes a dual-specificity phosphatase involved in the regulation of various signaling pathways. These cell lines are generated using advanced CRISPR/Cas9 gene-editing technology, effectively disrupting the DUSP13A gene and leading to its functional inactivation. The loss of DUSP13A activity allows researchers to examine its role in cellular processes, such as proliferation, apoptosis, and response to stress.
The primary function of DUSP13A is to dephosphorylate and inactivate MAPK (mitogen-activated protein kinase) pathways, which are crucial for cellular signaling and homeostasis. By utilizing DUSP13A knockout cell lines, scientists can investigate how the absence of this phosphatase affects MAPK signaling outcomes, contributing to our understanding of various disease mechanisms, including cancer and inflammatory disorders. This model holds significant value in both basic research and translational studies, facilitating the identification of potential therapeutic targets.
Compared to traditional knockdown approaches, our DUSP13A knockout cell lines provide a more robust and permanent genetic modification, leading to more consistent experimental results. Furthermore, these cell lines are available in multiple backgrounds, allowing for tailored experimental setups to fit diverse research needs.
By choosing DUSP13A Gene Knockout Cell Lines from our company, researchers benefit from high-quality, validated models that enhance the reliability of findings and accelerate the pace of discovery. Our dedication to providing cutting-edge biological products stems from years of expertise in gene editing technologies and cellular biology. Enhance your research capabilities and explore the intricate dynamics of DUSP13A regulation with our specialized cell lines, designed to empower scientific advancement and clinical innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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