Gene: DOK3
Official Full Name: docking protein 3provided by HGNC
Gene Summary: Predicted to be involved in Ras protein signal transduction; cell surface receptor protein tyrosine kinase signaling pathway; and positive regulation of MAPK cascade. Predicted to be located in ficolin-1-rich granule membrane and plasma membrane. Predicted to be active in cytoplasm. Implicated in colorectal adenocarcinoma. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18187 | DOK3 Knockout cell line (HeLa) | Human | DOK3 | 1:3~1:6 | Negative | Online Inquiry |
KO18188 | DOK3 Knockout cell line (HCT 116) | Human | DOK3 | 1:2~1:4 | Negative | Online Inquiry |
KO18189 | DOK3 Knockout cell line (HEK293) | Human | DOK3 | 1:3~1:6 | Negative | Online Inquiry |
KO18190 | DOK3 Knockout cell line (A549) | Human | DOK3 | 1:3~1:4 | Negative | Online Inquiry |
DOK3 Gene Knockout Cell Lines are specially engineered cells in which the DOK3 gene has been inactivated to facilitate the study of its biological role and associated pathways. DOK3, or Docking Protein 3, is known to play a pivotal role in various cellular processes, including cellular signaling, proliferation, and apoptosis. By employing CRISPR-Cas9 technology, these cell lines allow for precise gene knockout, enabling researchers to elucidate the functional consequences of DOK3 depletion on cellular behavior and molecular responses.
The key mechanism behind DOK3 Gene Knockout involves the targeted disruption of the DOK3 gene sequence, preventing the synthesis of functional DOK3 protein. This precise modification allows researchers to investigate the gene's implications in signal transduction pathways, particularly in contexts such as cancer biology, immunology, and metabolic disorders. The controlled environment of these knockout cell lines provides a unique platform not only for basic research but also for drug discovery and development, as they can be used to screen for potential therapeutic agents targeting signaling pathways affected by DOK3.
One significant advantage of utilizing DOK3 Gene Knockout Cell Lines is their ability to mimic pathophysiological conditions relevant to human diseases, making them indispensable tools in translational research. Compared to traditional methods of gene silencing, such as RNA interference, CRISPR-generated knockouts provide a more stable and permanent alteration of gene expression, thus offering clearer insights into long-term cellular functions. Researchers and clinicians seeking to understand the intricate biological roles of DOK3 can benefit from these cell lines, as they provide reliable data that can inform therapeutic strategies.
In summary, DOK3 Gene Knockout Cell Lines represent a critical resource for the scientific community, empowering researchers to unlock the complexities of DOK3 involvement in health and disease. Our company is committed to delivering high-quality, meticulously characterized biological products that support your research endeavors, leveraging years of industry expertise to provide solutions that enhance your scientific inquiries.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.