Gene: DNPEP
Official Full Name: aspartyl aminopeptidaseprovided by HGNC
Gene Summary: The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29154 | DNPEP Knockout cell line (HeLa) | Human | DNPEP | 1:3~1:6 | Negative | Online Inquiry |
KO29155 | DNPEP Knockout cell line (HCT 116) | Human | DNPEP | 1:2~1:4 | Negative | Online Inquiry |
KO29156 | DNPEP Knockout cell line (HEK293) | Human | DNPEP | 1:3~1:6 | Negative | Online Inquiry |
KO29157 | DNPEP Knockout cell line (A549) | Human | DNPEP | 1:3~1:4 | Negative | Online Inquiry |
DNPEP Gene Knockout Cell Lines are genetically engineered cellular models created to study the function and regulation of the DNPEP gene. This gene encodes for an enzyme involved in the metabolism of various bioactive peptides, playing a crucial role in processes such as cellular signaling and immune response modulation. Knockout cell lines have been constructed through CRISPR/Cas9 gene-editing technology, effectively disabling the DNPEP gene to provide researchers with a powerful tool for elucidating the biological pathways influenced by this enzyme.
The primary function of DNPEP Gene Knockout Cell Lines lies in their ability to facilitate in-depth investigations into peptide metabolism and its implications in various diseases. By silencing the DNPEP gene, researchers can observe the resultant cellular alterations, offering insights into the significance of peptide signaling in physiological and pathological states. This can lead to a better understanding of conditions such as cancer, neurodegenerative disorders, and metabolic diseases, where peptide functions are disrupted.
The scientific importance of these knockout cell lines extends to both basic research and clinical applications, enabling the development of therapeutic strategies targeting peptide-related pathways. Unlike traditional cell lines, the DNPEP knockout variants provide a controlled environment to observe the absence of the gene's expression, allowing for clearer interpretations of experimental results.
A key advantage of using DNPEP Gene Knockout Cell Lines is their specificity and reliability. With the precision afforded by CRISPR technology, these cell lines are designed to eliminate off-target effects, ensuring that experimental outcomes are solely attributed to the absence of DNPEP. They also enable high-throughput screening for potential drug candidates that may modulate peptide activity.
For researchers and clinicians looking to bridge the gap between fundamental biology and therapeutic application, these knockout cell lines offer an invaluable resource. Their development is backed by our company’s extensive expertise in genetic engineering and cellular biology, ensuring high-quality products that meet the rigorous demands of scientific inquiry.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.