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DNMBP Knockout Cell Lines

Gene: DNMBP

Official Full Name: dynamin binding proteinprovided by HGNC

Gene Summary: This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29552 DNMBP Knockout cell line (HeLa) Human DNMBP 1:3~1:6 Negative Online Inquiry
KO29553 DNMBP Knockout cell line (HCT 116) Human DNMBP 1:2~1:4 Negative Online Inquiry
KO29554 DNMBP Knockout cell line (HEK293) Human DNMBP 1:3~1:6 Negative Online Inquiry
KO29555 DNMBP Knockout cell line (A549) Human DNMBP 1:3~1:4 Negative Online Inquiry

Background

DNMBP Gene Knockout Cell Lines are genetically modified cellular systems that have been engineered to specifically disrupt the expression of the DNMBP (Death-associated protein kinase 1 and N-myc downstream-regulated gene 4-binding protein) gene. This product serves as a pivotal tool in understanding the functional role of DNMBP in various biological processes, particularly in cell proliferation, apoptosis, and differentiation. By employing CRISPR-Cas9 technology, these knockout cell lines create a precise disruption of the DNMBP gene, thus providing a robust platform for researchers to study the downstream effects of gene loss.

The key mechanisms underlying the functionality of DNMBP Gene Knockout Cell Lines include the complete abrogation of protein expression, allowing for the observation of phenotypic changes that result from the gene deletion. This can lead to a deeper understanding of the molecular pathways associated with DNMBP, including its influence on cancer progression and cellular stress responses. Such insights are invaluable for both research and clinical contexts, particularly in discerning the gene's role in disease states and therapeutic responses.

In the competitive arena of gene knockout technology, our DNMBP Gene Knockout Cell Lines stand out due to their high specificity and reproducibility. Unlike traditional methods that may yield off-target effects or variable knockout efficiencies, our cell lines have been meticulously validated to ensure reliability and accuracy. Furthermore, the ease of use and versatility in various experimental settings makes these lines an attractive option for researchers focused on gene function elucidation, pharmacology, and potential therapeutic development.

The importance of our DNMBP Gene Knockout Cell Lines lies not just in their technical precision but also in their potential applications in drug testing and development. Researchers can utilize these models to identify new therapeutic targets or to screen compounds that may restore normal function in the absence of DNMBP, ultimately translating findings into clinical advancements.

With a strong commitment to innovation and excellence in the field of biotechnology, our company offers unparalleled expertise and cutting-edge tools to empower researchers and clinicians alike. Our DNMBP Gene Knockout Cell Lines are not simply products, but essential resources in the quest to advance scientific understanding and therapeutic solutions in cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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