Gene: DIXDC1
Official Full Name: DIX domain containing 1provided by HGNC
Gene Summary: The protein encoded by this gene is a positive regulator of the Wnt signaling pathway. The encoded protein is found associated with gamma tubulin at the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24207 | DIXDC1 Knockout cell line (HeLa) | Human | DIXDC1 | 1:3~1:6 | Negative | Online Inquiry |
KO24208 | DIXDC1 Knockout cell line (HCT 116) | Human | DIXDC1 | 1:2~1:4 | Negative | Online Inquiry |
KO24209 | DIXDC1 Knockout cell line (HEK293) | Human | DIXDC1 | 1:3~1:6 | Negative | Online Inquiry |
KO24210 | DIXDC1 Knockout cell line (A549) | Human | DIXDC1 | 1:3~1:4 | Negative | Online Inquiry |
DIXDC1 Gene Knockout Cell Lines are specialized cellular models created through the targeted deletion of the DIXDC1 gene, which encodes a protein implicated in numerous signaling pathways and cellular mechanisms. These knockout cell lines are invaluable tools for researchers looking to investigate the functional roles of DIXDC1 in various physiological and pathological contexts, including cell proliferation, differentiation, and tumorigenesis.
The primary function of DIXDC1 is to facilitate Wnt signaling pathways and act as a scaffolding protein, influencing cellular responses to developmental cues. By utilizing DIXDC1 Gene Knockout Cell Lines, scientists can elucidate the precise impact of this gene on cellular behavior by comparing phenotypes with wild-type cell lines. The mechanisms at play include altered gene expression profiles, modified cell signaling cascades, and changes in cytoskeletal organization, all of which can be studied in detail to gain insights into the biological significance of DIXDC1.
In research and clinical settings, these knockout cell lines are crucial for applications related to cancer biology, regenerative medicine, and developmental studies. The ability to derive functional insights from these models can lead to novel therapeutic targets and strategies. Compared to traditional models, DIXDC1 Gene Knockout Cell Lines offer specificity in gene function analysis, enabling researchers to avoid the off-target effects often seen with pharmacological inhibitors or RNA interference techniques.
These cell lines represent a significant advancement for any laboratory focused on gene function studies, providing researchers and clinicians with the capability to conduct more accurate and targeted investigations. The high fidelity of these models underscores their value in the quest to understand complex biological systems and diseases.
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Please note that all services are for research use only. Not intended for any clinical use.
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