Gene: DHX30
Official Full Name: DExH-box helicase 30provided by HGNC
Gene Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The family member encoded by this gene is a mitochondrial nucleoid protein that associates with mitochondrial DNA. It has also been identified as a component of a transcriptional repressor complex that functions in retinal development, and it is required to optimize the function of the zinc-finger antiviral protein. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30154 | DHX30 Knockout cell line (HeLa) | Human | DHX30 | 1:3~1:6 | Negative | Online Inquiry |
KO30155 | DHX30 Knockout cell line (HCT 116) | Human | DHX30 | 1:2~1:4 | Negative | Online Inquiry |
KO30156 | DHX30 Knockout cell line (HEK293) | Human | DHX30 | 1:3~1:6 | Negative | Online Inquiry |
KO30157 | DHX30 Knockout cell line (A549) | Human | DHX30 | 1:3~1:4 | Negative | Online Inquiry |
DHX30 Gene Knockout Cell Lines are a sophisticated tool engineered to facilitate the study of the DHX30 gene's function within various biological pathways. These cell lines have been meticulously developed using CRISPR-Cas9 technology to create specific knockout models that allow researchers to investigate the role of DHX30 in cellular processes such as RNA metabolism, stress response, and immune regulation.
The key mechanism by which DHX30 Gene Knockout Cell Lines operate lies in the targeted disruption of the DHX30 gene, resulting in the absence of its encoded helicase activity. This disruption enables researchers to analyze how the loss of DHX30 affects gene expression, cell proliferation, and other critical cellular functions. With DHX30 being implicated in various diseases, including cancer and autoimmune disorders, these knockout lines offer invaluable insights into the underlying molecular mechanisms by enabling gene function analysis in a controlled environment.
From a scientific standpoint, the applications of these knockout cell lines in research are profound. They are utilized in pharmacological studies, enabling the screening of potential therapeutics that may target pathways involving DHX30. In clinical settings, understanding the implications of DHX30 loss can lead to novel biomarker discovery and the development of targeted therapies, thus advancing personalized medicine.
What sets DHX30 Gene Knockout Cell Lines apart from alternative models is their specificity, reliability, and the technical support provided by our team, ensuring that users can achieve optimal results. Our commitment to quality and innovation enhances the value of these products, making them crucial for any laboratory focused on genetic research and therapeutic development.
In conclusion, investing in DHX30 Gene Knockout Cell Lines not only provides researchers and clinicians with a cutting-edge resource for genetic studies, but it also affirms our company's expertise in developing high-quality, biologically relevant products designed to expedite scientific discovery and innovation in the field of molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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