Gene: DHTKD1
Official Full Name: dehydrogenase E1 and transketolase domain containing 1provided by HGNC
Gene Summary: This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids, including lysine. Mutations in this gene are associated with 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth Disease Type 2Q. [provided by RefSeq, May 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18295 | DHTKD1 Knockout cell line (HeLa) | Human | DHTKD1 | 1:3~1:6 | Negative | Online Inquiry |
KO18296 | DHTKD1 Knockout cell line (HCT 116) | Human | DHTKD1 | 1:2~1:4 | Negative | Online Inquiry |
KO18297 | DHTKD1 Knockout cell line (HEK293) | Human | DHTKD1 | 1:3~1:6 | Negative | Online Inquiry |
KO18298 | DHTKD1 Knockout cell line (A549) | Human | DHTKD1 | 1:3~1:4 | Negative | Online Inquiry |
DHTKD1 Gene Knockout Cell Lines are genetically modified cell lines in which the DHTKD1 gene has been selectively disrupted, enabling researchers to investigate the biological functions and roles of this particular gene in various cellular processes. DHTKD1 (dihydrotachysterol kinase domain-containing protein 1) plays a crucial role in metabolic pathways, particularly in the context of mitochondrial function and energy metabolism. By creating knockout models, scientists can study the physiological effects of DHTKD1 deficiency, elucidating its impact on metabolic dysregulation and disease states.
The primary function of these cell lines lies in their ability to facilitate research into the mechanistic pathways influenced by DHTKD1. The absence of this gene allows for a clearer observation of metabolic shifts, disruptions in mitochondrial dynamics, and altered cellular responses to stress signals. Researchers can utilize these cell lines to probe the underlying mechanisms of diseases such as mitochondrial disorders, obesity, and other metabolic syndromes, thereby contributing critical insights for potential therapeutic developments.
In clinical and research settings, DHTKD1 Gene Knockout Cell Lines represent a valuable tool for generating in-depth knowledge on gene function and disease modeling. Existing alternatives, such as RNA interference or CRISPR interference technologies, often result in incomplete gene modulation or off-target effects, whereas our knockout cell lines provide a definitive genetic alteration, ensuring more precise experimental outcomes.
The advantages of using DHTKD1 Gene Knockout Cell Lines include a clean genetic background allowing for straightforward analysis, the potential for high-throughput screening, and the capacity for easier validation of experimental results. These attributes make them indispensable for researchers focused on innovative metabolic studies and drug discovery.
Investing in our DHTKD1 Gene Knockout Cell Lines not only enhances the robustness of your experimental design but also deepens your understanding of metabolic pathways critical for human health. With our commitment to providing high-quality biological products and expertise in genomic technologies, our company stands at the forefront of advancing scientific research and therapeutic innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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