Gene: DGCR6L
Official Full Name: DiGeorge syndrome critical region gene 6 likeprovided by HGNC
Gene Summary: This gene, the result of a duplication at this locus, is one of two functional genes encoding nearly identical proteins that have similar expression patterns. The product of this gene is a protein that shares homology with the Drosophila gonadal protein, expressed in gonadal tissues and germ cells, and with the human laminin gamma-1 chain that functions in cell attachment and migration. This gene is located in a region of chromosome 22 implicated in the DiGeorge syndrome, one facet of a broader collection of anomalies referred to as the CATCH 22 syndrome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24270 | DGCR6L Knockout cell line (HeLa) | Human | DGCR6L | 1:3~1:6 | Negative | Online Inquiry |
KO24271 | DGCR6L Knockout cell line (HCT 116) | Human | DGCR6L | 1:2~1:4 | Negative | Online Inquiry |
KO24272 | DGCR6L Knockout cell line (HEK293) | Human | DGCR6L | 1:3~1:6 | Negative | Online Inquiry |
KO24273 | DGCR6L Knockout cell line (A549) | Human | DGCR6L | 1:3~1:4 | Negative | Online Inquiry |
DGCR6L Gene Knockout Cell Lines are meticulously engineered cellular models that facilitate the study of the DGCR6L gene's role in various biological processes and pathologies. The DGCR6L gene, known for its significance in the context of certain genetic disorders and cancer biology, has been systematically knocked out using advanced CRISPR-Cas9 gene-editing technology. This knockout allows researchers to investigate the gene's function and its impact on cellular mechanisms, including proliferation, differentiation, and apoptosis.
These cell lines exhibit altered phenotypic characteristics that provide a platform for exploring the molecular pathways influenced by DGCR6L. This is particularly relevant for drug discovery and the development of targeted therapies, as researchers can evaluate the effects of therapeutics on cells lacking this gene. Additionally, knockout models are crucial for understanding genetic interactions and the broader implications of gene dysregulation in disease states.
The scientific importance of DGCR6L Gene Knockout Cell Lines cannot be overstated, as they can elucidate the gene's involvement in congenital syndromes associated with deletions on chromosome 22, such as DiGeorge syndrome. Compared to alternative models, such as wild-type cell lines or other knockout models, our DGCR6L cell lines provide a higher resolution understanding of gene function due to their specificity and targeted modifications.
For researchers and clinicians, the unique selling points of these cell lines include ease of use, reproducibility, and comprehensive characterization data, which supports rigorous experimental design. Moreover, as a product of our extensive expertise in molecular biology and genetics, customers can trust that these knockout cell lines are not only reliable but also reflect the highest standards of quality and validation.
The DGCR6L Gene Knockout Cell Lines empower researchers with critical insights that are essential for advancing knowledge in genetics, pharmacology, and cellular biology, making them a valuable asset in contemporary biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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