Gene: DELE1
Official Full Name: DAP3 binding cell death enhancer 1provided by HGNC
Gene Summary: Enables protein kinase binding activity and protein serine/threonine kinase activator activity. Involved in several processes, including HRI-mediated signaling; positive regulation of mitophagy; and response to iron ion starvation. Located in mitochondrial inner membrane. Is active in cytosol and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32730 | DELE1 Knockout cell line (HeLa) | Human | DELE1 | 1:3~1:6 | Negative | Online Inquiry |
KO32731 | DELE1 Knockout cell line (HCT 116) | Human | DELE1 | 1:2~1:4 | Negative | Online Inquiry |
KO32732 | DELE1 Knockout cell line (HEK293) | Human | DELE1 | 1:3~1:6 | Negative | Online Inquiry |
KO32733 | DELE1 Knockout cell line (A549) | Human | DELE1 | 1:3~1:4 | Negative | Online Inquiry |
DELE1 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to lack the DELE1 gene, a key regulator implicated in cellular stress responses and inflammation. These knockout models provide researchers with a valuable tool for studying the functional roles of DELE1 in various biological processes, including immune response, apoptosis, and metabolic regulation. By utilizing CRISPR-Cas9 gene editing technology, the DELE1 gene has been precisely disrupted, allowing for in-depth investigations into the pathways mediated by this gene and its effect on cellular phenotypes.
In terms of functionality, the DELE1 Knockout Cell Lines enable the elucidation of mechanisms underlying stress-induced cellular pathways. As DELE1 is known to facilitate mitochondrial stress signaling, these cell lines can be instrumental in studying mitochondrial dynamics and the cellular response to oxidative stress. Furthermore, understanding the roles of DELE1 in cancer and metabolic disorders can pave the way for novel therapeutic strategies targeting these pathways.
The scientific importance of DELE1 Gene Knockout Cell Lines cannot be understated, as they support a range of applications in both basic research and clinical settings. Researchers can employ these cell lines to investigate the gene's contribution to diseases associated with inflammation and metabolic dysregulation, thereby opening avenues for targeted drug development and personalized medicine approaches.
What sets DELE1 Gene Knockout Cell Lines apart from traditional cell lines or alternative knockout models is their exceptional specificity and reliability. Given the precision of CRISPR technology, researchers can be confident in the fidelity of the knockout, ensuring reproducible results that are crucial for upstream drug discovery and downstream translational applications.
This unique product not only enhances the understanding of complex biological pathways but also empowers researchers and clinicians by simplifying the investigation of gene function and pathology. By integrating DELE1 Gene Knockout Cell Lines into their research, users can gain insightful data that may lead to pivotal advances in treatment methodologies.
Backed by our company's extensive experience in the development of high-quality biological products and cutting-edge gene editing technologies, we are committed to providing researchers with tools that enhance their capabilities and drive innovation within the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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